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A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.

ENZYME entry: EC

Accepted Name
Tetracenomycin F2 synthase.
Reaction catalysed
10 malonyl-CoA <=> tetracenomycin F2 + 10 CoA + 10 CO(2) + 2 H(2)O
  • A multi-domain polyketide synthase involved in the synthesis of tetracenomycin in the bacterium Streptomyces glaucescens.
  • It involves a ketosynthase complex, an acyl carrier protein, a malonyl CoA:ACP acyltransferase, and a cyclase.
  • A malonyl-CoA molecule is initially bound to the acyl carrier protein and decarboxylated to form an acetyl starter unit.
  • Additional two-carbon units are added from nine more malonyl-CoA molecules.
PRIAM enzyme-specific profiles2.3.1.235
KEGG Ligand Database for Enzyme Nomenclature2.3.1.235
IUBMB Enzyme Nomenclature2.3.1.235
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