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ENZYME entry: EC 2.3.1.235
| Accepted Name |
|---|
| tetracenomycin F2 synthase.
|
| Reaction catalysed |
|---|
| 8 H(+) + 10 malonyl-CoA <=> 10 CO2 + 10 CoA + 2 H2O + tetracenomycin F2 |
| Comment(s) |
|---|
- A multi-domain polyketide synthase involved in the synthesis of
tetracenomycin in the bacterium Streptomyces glaucescens.
- It involves a ketosynthase complex, an acyl carrier protein,
a malonyl CoA:ACP acyltransferase, and a cyclase.
- A malonyl-CoA molecule is initially bound to the acyl carrier protein
and decarboxylated to form an acetyl starter unit.
- Additional two-carbon units are added from nine more malonyl-CoA
molecules.
|
| Cross-references |
|---|
| BRENDA | 2.3.1.235 |
| EC2PDB | 2.3.1.235 |
| ExplorEnz | 2.3.1.235 |
| PRIAM enzyme-specific profiles | 2.3.1.235 |
| KEGG Ligand Database for Enzyme Nomenclature | 2.3.1.235 |
| IUBMB Enzyme Nomenclature | 2.3.1.235 |
| IntEnz | 2.3.1.235 |
| MEDLINE | Find literature relating to 2.3.1.235 |
| MetaCyc | 2.3.1.235 |
| Rhea expert-curated reactions | 2.3.1.235 |
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All
ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 2.3.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.3.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-