Expasy logo


ENZYME entry: EC

Accepted Name
acyl-[acyl-carrier protein]--UDP-2-acetamido-3-amino-2,3-dideoxy-alpha-D- glucopyranose N-acyltransferase
Reaction catalysed
a (3R)-hydroxyacyl-[ACP] + UDP-2-acetamido-3-amino-2,3-dideoxy-alpha-D-glucopyranose <=> a UDP-2-acetamido-3-{[(3R)-3-hydroxyacyl]amino}-2,3-dideoxy-alpha-D-glucopyranose + H(+) + holo-[ACP]
  • The enzyme is found in bacterial species whose lipid A contains 2,3- diamino-2,3-dideoxy-D-glucopyranose.
  • Some enzymes, such as that from Leptospira interrogans, are highly specific for 2,3-diamino-2,3-dideoxy-D-glucopyranose, while others, such as the enzyme from Acidithiobacillus ferrooxidans, are also able to accept UDP-N-acetyl-alpha-D-glucosamine (cf. EC
  • The enzymes from different organisms also differ in their specificity for the acyl donor. The enzyme from L. interrogans is highly specific for (3R)-3-hydroxydodecanoyl-[acyl-carrier protein], while that from Mesorhizobium loti functions almost equally well with 10-, 12-, and 14-carbon 3-hydroxyacyl-[acyl-carrier protein]s.
PRIAM enzyme-specific profiles2.3.1.305
KEGG Ligand Database for Enzyme Nomenclature2.3.1.305
IUBMB Enzyme Nomenclature2.3.1.305
MEDLINEFind literature relating to
Rhea expert-curated reactions2.3.1.305

View entry in original ENZYME format
View entry in raw text format (no links)
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.3.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.3.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-