ENZYME entry: EC 2.3.1.43
Accepted Name |
Phosphatidylcholine--sterol O-acyltransferase.
|
Alternative Name(s) |
LCAT. |
Lecithin--cholesterol acyltransferase. |
Phospholipid--cholesterol acyltransferase. |
Reaction catalysed |
Phosphatidylcholine + a sterol <=> 1-acylglycerophosphocholine + a sterol ester |
Comment(s) |
- Palmitoyl, oleoyl, and linoleoyl can be transferred; a number of
sterols, including cholesterol, can act as acceptors.
- The bacterial enzyme also catalyzes the reactions of EC 3.1.1.4 and
EC 3.1.1.5.
|
Cross-references |
PROSITE | PDOC00110 |
BRENDA | 2.3.1.43 |
EC2PDB | 2.3.1.43 |
ExplorEnz | 2.3.1.43 |
PRIAM enzyme-specific profiles | 2.3.1.43 |
KEGG Ligand Database for Enzyme Nomenclature | 2.3.1.43 |
IUBMB Enzyme Nomenclature | 2.3.1.43 |
IntEnz | 2.3.1.43 |
MEDLINE | Find literature relating to 2.3.1.43 |
MetaCyc | 2.3.1.43 |
UniProtKB/Swiss-Prot |
P10480, GCAT_AERHY; | P53760, LCAT_CHICK; | O35573, LCAT_ELIQU; |
O35840, LCAT_GERGM; | P04180, LCAT_HUMAN; | O35724, LCAT_MICMN; |
P16301, LCAT_MOUSE; | O35502, LCAT_MYOGA; | Q08758, LCAT_PAPAN; |
P30930, LCAT_PIG; | P53761, LCAT_RABIT; | P18424, LCAT_RAT; |
|
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ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 2.3.1.-
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