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ENZYME entry: EC 2.3.3.19

Accepted Name
2-phosphonomethylmalate synthase.
Alternative Name(s)
2-phosphinomethylmalic acid synthase.
PMM synthase.
Reaction catalysed
3-phosphonopyruvate + acetyl-CoA + H(2)O <=> (R)-2-(phosphonomethyl)malate + CoA
Comment(s)
  • The enzyme, isolated from several Streptomyces species, participates in the biosynthesis of certain phosphonate antibiotics.
  • The enzyme is analogous to EC 2.3.3.1.
Cross-references
BRENDA2.3.3.19
EC2PDB2.3.3.19
ExplorEnz2.3.3.19
PRIAM enzyme-specific profiles2.3.3.19
KEGG Ligand Database for Enzyme Nomenclature2.3.3.19
IUBMB Enzyme Nomenclature2.3.3.19
IntEnz2.3.3.19
MEDLINEFind literature relating to 2.3.3.19
MetaCyc2.3.3.19
UniProtKB/Swiss-Prot
Q0ZQ46, FRBC_STRR3

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