ENZYME entry: EC 2.4.1.245
Accepted Name |
Alpha,alpha-trehalose synthase.
|
Alternative Name(s) |
Trehalose synthase. |
Trehalose synthetase. |
Reaction catalysed |
NDP-alpha-D-glucose + D-glucose <=> alpha,alpha-trehalose + NDP |
Cofactor(s) |
Mg(2+).
|
Comment(s) |
- The enzyme-catalyzed reaction is reversible.
- In the reverse direction to that shown above, the enzyme is specific
for alpha,alpha-trehalose as substrate, as it cannot use alpha- or
beta-paranitrophenyl glucosides, maltose, sucrose, lactose or
cellobiose.
- While the enzymes from the thermophilic bacterium Rubrobacter
xylanophilus and the hyperthermophilic archaeon Pyrococcus horikoshii
can use ADP-, UDP- and GDP-alpha-D-glucose to the same extent, that
from the hyperthermophilic archaeon Thermococcus litoralis has a
marked preference for ADP-alpha-D-glucose and that from the
hyperthermophilic archaeon Thermoproteus tenax has a marked
preference for UDP-alpha-D-glucose.
- Formerly EC 2.4.1.n1.
|
Cross-references |
BRENDA | 2.4.1.245 |
EC2PDB | 2.4.1.245 |
ExplorEnz | 2.4.1.245 |
PRIAM enzyme-specific profiles | 2.4.1.245 |
KEGG Ligand Database for Enzyme Nomenclature | 2.4.1.245 |
IUBMB Enzyme Nomenclature | 2.4.1.245 |
IntEnz | 2.4.1.245 |
MEDLINE | Find literature relating to 2.4.1.245 |
MetaCyc | 2.4.1.245 |
Rhea expert-curated reactions | 2.4.1.245 |
UniProtKB/Swiss-Prot |
|
View entry in original ENZYME format
View entry in raw text format (no links)
All
ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 2.4.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.4.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-