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ENZYME

ENZYME entry: EC 2.4.1.38

PURL: https://purl.expasy.org/enzyme/EC/2.4.1.38
Accepted Name
beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase
Alternative Name(s)
GalT
glycoprotein 4-beta-galactosyltransferase
thyroid galactosyltransferase
UDP-galactose--glycoprotein galactosyltransferase
Reaction catalysed
an N-acetyl-beta-D-glucosaminyl derivative + UDP-alpha-D-galactose = a beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + UDP + H(+)
Comment(s)
  • Terminal N-acetyl-beta-D-glucosaminyl residues in polysaccharides, glycoproteins and glycopeptides can act as acceptor.
  • High activity is shown toward such residues in branched-chain polysaccharides when these are linked by beta-1,6 links to galactose residues; lower activity toward residues linked to galactose by beta- 1,3 links.
  • A component of EC 2.4.1.22.
Cross-references
BRENDA2.4.1.38
EC2PDB2.4.1.38
ExplorEnz2.4.1.38
KEGG Ligand Database for Enzyme Nomenclature2.4.1.38
IUBMB Enzyme Nomenclature2.4.1.38
MEDLINEFind literature relating to 2.4.1.38
MetaCyc2.4.1.38
Rhea expert-curated reactions2.4.1.38
UniProtKB/Swiss-Prot
P08037, B4GT1_BOVINP15291, B4GT1_HUMANP15535, B4GT1_MOUSE
P80225, B4GT1_RATQ80WN9, B4GT2_CRIGRO60909, B4GT2_HUMAN
Q9Z2Y2, B4GT2_MOUSEQ5EA87, B4GT3_BOVINQ80WN8, B4GT3_CRIGR
O60512, B4GT3_HUMANQ91YY2, B4GT3_MOUSEQ5NVN3, B4GT3_PONAB
Q6P768, B4GT3_RAT

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.4.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.4.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-