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|alpha(1,3/1,4) fucosyltransferase III.|
|blood group Lewis alpha-4-fucosyltransferase.|
|blood-group substance Le(a)-dependent fucosyltransferase.|
|guanosine diphosphofucose-beta-acetylglucosaminylsaccharide 4-alpha-L-
|guanosine diphosphofucose-glycoprotein 4-alpha-fucosyltransferase.|
|guanosine diphosphofucose-glycoprotein 4-alpha-L-fucosyltransferase.|
|Lewis(Le) blood group gene-dependent alpha-(1->3/4)-L-fucosyltransferase.|
|Lewis blood group alpha-(1->3/4)-fucosyltransferase.|
|a beta-D-galactosyl-(1->3)-N-acetyl-beta-D-glucosaminyl derivative + GDP-beta-L-fucose <=> a beta-D-galactosyl-(1->3)-[alpha-L-fucosyl-(1->4)]-N-acetyl-beta-D-glucosaminyl derivative + GDP + H(+)|
- Product of the Lewis blood group gene.
- Normally acts on a glycoconjugate where R (see CA line) is a
glycoprotein or glycolipid.
- Although it is a 4-fucosyltransferase, it has a persistent
3-fucosyltransferase activity toward the glucose residue in free
- Fucosylates on O-4 of an N-acetylglucosamine that carries a
galactosyl group on O-3, unlike EC 22.214.171.124 which fucosylates on O-3
of an N-acetylglucosamine that carries a galactosyl group on O-4.
- Enzymes catalyzing the 4-alpha-fucosylation of the GlcNAc in beta-D-
Gal-(1->3)-beta-GlcNAc sequences (with some activity also as 3-alpha-
fucosyltransferases) are present in plants, where the function in
vivo is the modification of N-glycans.
- In addition, the fucTa gene of Helicobacter strain UA948 encodes a
fucosyltransferase with both 3-alpha- and 4-alpha-fucosyltransferase
|PRIAM enzyme-specific profiles||126.96.36.199|
|KEGG Ligand Database for Enzyme Nomenclature||188.8.131.52|
|IUBMB Enzyme Nomenclature||184.108.40.206|
|MEDLINE||Find literature relating to 220.127.116.11|
|Rhea expert-curated reactions||18.104.22.168|
|Q11126, FUT3_BOVIN; ||P21217, FUT3_HUMAN; ||O19058, FUT3_PANTR; |
|Q8HYJ5, FUT3_PONPY; ||Q8HYJ7, FUT5_GORGO; ||Q11128, FUT5_HUMAN; |
|Q8HYJ3, FUT5_HYLLA; ||P56433, FUT5_PANTR; ||Q8HYJ4, FUT5_PONPY; |
|G5EFP5, FUTC_CAEEL; ||G5EE06, FUTD_CAEEL; |