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ENZYME entry: EC 2.4.1.68
Accepted Name |
glycoprotein 6-alpha-L-fucosyltransferase.
|
Alternative Name(s) |
GDP-fucose--glycoprotein fucosyltransferase. |
GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha(1->6)fucosyltransferase. |
GDP-L-fucose-glycoprotein fucosyltransferase. |
glycoprotein fucosyltransferase. |
guanosine diphosphofucose-glycoprotein fucosyltransferase. |
Reaction catalysed |
GDP-beta-L-fucose + N(4)-{beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)-[beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc}-L-asparaginyl-[protein] <=> GDP + H(+) + N(4)-{beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)-[beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAcl-(1->4)-[alpha-L-Fuc-(1->6)]-beta-D-GlcNAc}-L-asparaginyl-[protein] |
Comment(s) |
Catalyzes a reaction similar to that of EC 2.4.1.214, but transfers
the L-fucosyl group from GDP-beta-L-fucose to form an alpha-1,6-
linkage rather than an alpha-1,3-linkage.
|
Cross-references |
BRENDA | 2.4.1.68 |
EC2PDB | 2.4.1.68 |
ExplorEnz | 2.4.1.68 |
PRIAM enzyme-specific profiles | 2.4.1.68 |
KEGG Ligand Database for Enzyme Nomenclature | 2.4.1.68 |
IUBMB Enzyme Nomenclature | 2.4.1.68 |
IntEnz | 2.4.1.68 |
MEDLINE | Find literature relating to 2.4.1.68 |
MetaCyc | 2.4.1.68 |
Rhea expert-curated reactions | 2.4.1.68 |
UniProtKB/Swiss-Prot |
Q9N0W2, FUT8_BOVIN; | G5EFE7, FUT8_CAEEL; | Q659X0, FUT8_CANLF; |
Q9VYV5, FUT8_DROME; | Q9BYC5, FUT8_HUMAN; | Q9WTS2, FUT8_MOUSE; |
Q6EV77, FUT8_PANTR; | P79282, FUT8_PIG; | Q5NVB3, FUT8_PONAB; |
Q6EV76, FUT8_RAT; | Q6NVP8, FUT8_XENTR; |
|
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ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 2.4.1.-
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