ENZYME entry: EC 2.4.1.68
| Accepted Name | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| glycoprotein 6-alpha-L-fucosyltransferase | ||||||||||||
| Alternative Name(s) | ||||||||||||
| GDP-fucose--glycoprotein fucosyltransferase | ||||||||||||
| GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha(1->6)fucosyltransferase | ||||||||||||
| GDP-L-fucose-glycoprotein fucosyltransferase | ||||||||||||
| glycoprotein fucosyltransferase | ||||||||||||
| guanosine diphosphofucose-glycoprotein fucosyltransferase | ||||||||||||
| Reaction catalysed | ||||||||||||
| GDP-beta-L-fucose + N(4)-{beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)-[beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc}-L-asparaginyl-[protein] <=> GDP + H(+) + N(4)-{beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)-[beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-[alpha-L-Fuc-(1->6)]-beta-D-GlcNAc}-L-asparaginyl-[protein] | ||||||||||||
| Comment(s) | ||||||||||||
| Catalyzes a reaction similar to that of EC 2.4.1.214, but transfers the L-fucosyl group from GDP-beta-L-fucose to form an alpha-1,6- linkage rather than an alpha-1,3-linkage. | ||||||||||||
| Cross-references | ||||||||||||
| BRENDA | 2.4.1.68 | |||||||||||
| EC2PDB | 2.4.1.68 | |||||||||||
| ExplorEnz | 2.4.1.68 | |||||||||||
| PRIAM enzyme-specific profiles | 2.4.1.68 | |||||||||||
| KEGG Ligand Database for Enzyme Nomenclature | 2.4.1.68 | |||||||||||
| IUBMB Enzyme Nomenclature | 2.4.1.68 | |||||||||||
| IntEnz | 2.4.1.68 | |||||||||||
| MEDLINE | Find literature relating to 2.4.1.68 | |||||||||||
| MetaCyc | 2.4.1.68 | |||||||||||
| Rhea expert-curated reactions | 2.4.1.68 | |||||||||||
| UniProtKB/Swiss-Prot |
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