| Accepted Name |
|---|
| type 1 galactoside alpha-(1,2)-fucosyltransferase.
|
| Alternative Name(s) |
|---|
| alpha-(1->2)-L-fucosyltransferase. |
| alpha-2-fucosyltransferase. |
| alpha-2-L-fucosyltransferase. |
| beta-galactoside alpha1->2 fucosyltransferase. |
| blood group H alpha-2-fucosyltransferase. |
| blood-group substance H-dependent fucosyltransferase. |
| galactoside 2-alpha-L-fucosyltransferase. |
| guanosine diphosphofucose-beta-D-galactosyl-alpha-2-L-fucosyltransferase. |
| guanosine diphosphofucose-galactoside 2-L-fucosyltransferase. |
| guanosine diphosphofucose-
galactosylacetylglucosaminylgalactosylglucosylceramide alpha-L-
fucosyltransferase. |
| guanosine diphosphofucose-glycoprotein 2-alpha-fucosyltransferase. |
| guanosine diphosphofucose-glycoprotein 2-alpha-L-fucosyltransferase. |
| secretor-type beta-galactoside alpha1->2 fucosyltransferase. |
| Reaction catalysed |
|---|
| a beta-D-galactosyl-(1->3)-N-acetyl-beta-D-glucosaminyl derivative + GDP-beta-L-fucose <=> an alpha-L-Fuc-(1->2)-beta-D-Gal-(1->3)-beta-D-GlcNAc derivative + GDP + H(+) |
| Comment(s) |
|---|
- The enzyme acts on a glycoconjugates where the substituent group is a
glycoprotein or glycosphingolipid.
- The recognized moiety of the substrate is known as a type 1 histo-
blood group antigen precursor disaccharide, and the action of the
enzyme produces an H type 1 antigen.
- The enzyme from the bacterium Helicobacter pylori cannot act on type
2 substrates (see EC 2.4.1.344).
- Formerly EC 2.4.1.89.
|
| Cross-references |
|---|
| BRENDA | 2.4.1.69 |
| EC2PDB | 2.4.1.69 |
| ExplorEnz | 2.4.1.69 |
| PRIAM enzyme-specific profiles | 2.4.1.69 |
| KEGG Ligand Database for Enzyme Nomenclature | 2.4.1.69 |
| IUBMB Enzyme Nomenclature | 2.4.1.69 |
| IntEnz | 2.4.1.69 |
| MEDLINE | Find literature relating to 2.4.1.69 |
| MetaCyc | 2.4.1.69 |
| Rhea expert-curated reactions | 2.4.1.69 |
| UniProtKB/Swiss-Prot |
| Q866E1, FUT1_ALOBE; | Q866E4, FUT1_ALOCA; | Q866E6, FUT1_AOTAZ; |
| Q866E7, FUT1_AOTNA; | Q866C7, FUT1_ATEBE; | F6Q1T7, FUT1_BOVIN; |
| Q9TUD4, FUT1_GORGO; | P19526, FUT1_HUMAN; | Q866C9, FUT1_LAGLA; |
| Q866D6, FUT1_LEOCY; | Q866D2, FUT1_LEOFU; | Q866D9, FUT1_MICHU; |
| O09160, FUT1_MOUSE; | Q9TUD6, FUT1_PANTR; | Q29043, FUT1_PIG; |
| Q866C5, FUT1_PLEBR; | Q10979, FUT1_RABIT; | Q10980, FUT1_RAT; |
| Q866F0, FUT1_SAIBB; | Q866F1, FUT1_SAISC; | Q866E8, FUT1_SAPAP; |
| Q28113, FUT2_BOVIN; | O77486, FUT2_GORGO; | Q10981, FUT2_HUMAN; |
| Q9TTC7, FUT2_HYLLA; | Q9JL27, FUT2_MOUSE; | O77485, FUT2_PANTR; |
| Q10982, FUT2_PIG; | O77487, FUT2_PONPY; | Q10983, FUT2_RABIT; |
| Q10984, FUT2_RAT; | Q54QG0, PGFB_DICDI; |
|