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ENZYME

ENZYME entry: EC 2.4.2.48

Accepted Name
tRNA-guanine(15) transglycosylase
Alternative Name(s)
transfer ribonucleic acid guanine(15) transglycosylase
tRNA guanine(15) transglycosidase
Reaction catalysed
guanosine(15) in tRNA + 7-cyano-7-deazaguanine = 7-cyano-7-carbaguanosine(15) in tRNA + guanine
Comment(s)
  • Archaeal tRNAs contain the modified nucleoside archaeosine at position 15.
  • This archaeal enzyme catalyzes the exchange of guanine at position 15 of tRNA with the base preQ0, which is ultimately modified to form the nucleoside archaeosine (cf. EC 2.6.1.97).
Cross-references
BRENDA2.4.2.48
EC2PDB2.4.2.48
ExplorEnz2.4.2.48
PRIAM enzyme-specific profiles2.4.2.48
KEGG Ligand Database for Enzyme Nomenclature2.4.2.48
IUBMB Enzyme Nomenclature2.4.2.48
IntEnz2.4.2.48
MEDLINEFind literature relating to 2.4.2.48
MetaCyc2.4.2.48
Rhea expert-curated reactions2.4.2.48
UniProtKB/Swiss-Prot
Q9YAC2, ATGT_AERPEO29667, ATGT_ARCFUQ5UXP9, ATGT_HALMA
Q9HNT1, ATGT_HALSAQ9C4M3, ATGT_HALVDB1L6M8, ATGT_KORCO
A6UVD8, ATGT_META3Q8THU2, ATGT_METACQ46DI6, ATGT_METBF
Q2FUA5, ATGT_METHJQ57878, ATGT_METJAQ8TYV3, ATGT_METKA
A4FYL8, ATGT_METM5A9A6B5, ATGT_METM6A6VJR4, ATGT_METM7
Q8PXW5, ATGT_METMAQ6LZL5, ATGT_METMPA5UNI4, ATGT_METS3
Q2NGY4, ATGT_METSTO26278, ATGT_METTHA6USA4, ATGT_METVS
Q74N90, ATGT_NANEQQ3IR98, ATGT_NATPDQ6L1W3, ATGT_PICTO
Q9UZN0, ATGT_PYRABQ8ZYH2, ATGT_PYRAEQ8TH08, ATGT_PYRFU
O58843, ATGT_PYRHOQ980L7, ATGT_SACS2Q4JAY6, ATGT_SULAC
Q975U5, ATGT_SULTOQ9HI54, ATGT_THEACQ5JHC0, ATGT_THEKO
B6YUR8, ATGT_THEONQ977Z3, ATGT_THEVO

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.4.2.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.4.-.-
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