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ENZYME entry: EC 2.4.2.63

Accepted Name
EGF-domain serine xylosyltransferase.
Reaction catalysed
UDP-alpha-D-xylose + [protein with EGF-like domain]-L-serine <=> UDP + [protein with EGF-like domain]-3-O-(beta-D-xylosyl)-L-serine
Comment(s)
  • The enzyme, found in animals and insects, xylosylates at the serine in the C-X-S-X-P-C motif of epidermal growth factor-like (EGF-like) domains.
  • The enzyme is bifunctional also being active with UDP-alpha-glucose as donor (EC 2.4.1.376).
Cross-references
BRENDA2.4.2.63
EC2PDB2.4.2.63
ExplorEnz2.4.2.63
PRIAM enzyme-specific profiles2.4.2.63
KEGG Ligand Database for Enzyme Nomenclature2.4.2.63
IUBMB Enzyme Nomenclature2.4.2.63
IntEnz2.4.2.63
MEDLINEFind literature relating to 2.4.2.63
MetaCyc2.4.2.63
Rhea expert-curated reactions2.4.2.63
UniProtKB/Swiss-Prot
Q5E9Q1, PGLT1_BOVIN;  Q8NBL1, PGLT1_HUMAN;  Q8BYB9, PGLT1_MOUSE;  
G3V9D0, PGLT1_RAT;  

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