A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.

ENZYME entry: EC 2.4.99.3

Accepted Name
Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase.
Alternative Name(s)
GalNAc alpha-2,6-sialyltransferase I.
Reaction catalysed
CMP-N-acetylneuraminate + glycano-(1->3)-(N-acetyl-alpha-D-galactosaminyl)-glycoprotein <=> CMP + glycano-((2->6)-alpha-N-acetylneuraminyl)-(N-acetyl-D-galactosaminyl)-glycoprotein
Comment(s)
Alpha-N-acetylgalactosamine linked to threonine or serine is also an acceptor, when substituted at the 3-position.
Cross-references
BRENDA2.4.99.3
EC2PDB2.4.99.3
ExplorEnz2.4.99.3
PRIAM enzyme-specific profiles2.4.99.3
KEGG Ligand Database for Enzyme Nomenclature2.4.99.3
IUBMB Enzyme Nomenclature2.4.99.3
IntEnz2.4.99.3
MEDLINEFind literature relating to 2.4.99.3
MetaCyc2.4.99.3
UniProtKB/Swiss-Prot
Q92183, SIA7A_CHICK;  Q9NSC7, SIA7A_HUMAN;  Q9QZ39, SIA7A_MOUSE;  
Q92184, SIA7B_CHICK;  Q9UJ37, SIA7B_HUMAN;  P70277, SIA7B_MOUSE;  

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