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ENZYME

ENZYME entry: EC 2.5.1.115

PURL: https://purl.expasy.org/enzyme/EC/2.5.1.115
Accepted Name
homogentisate phytyltransferase
Alternative Name(s)
HPT
Reaction catalysed
phytyl diphosphate + homogentisate + H(+) = 2-methyl-6-phytyl-1,4-benzene-1,4-diol + CO2 + diphosphate
Comment(s)
  • Involved in the biosynthesis of the vitamin E tocopherols.
  • While the enzyme from the cyanobacterium Synechocystis PCC 6803 has an appreciable activity with geranylgeranyl diphosphate (EC 2.5.1.116), the enzyme from the plant Arabidopsis thaliana has only a low activity with that substrate.
  • Formerly EC 2.5.1.n8.
Cross-references
BRENDA2.5.1.115
EC2PDB2.5.1.115
ExplorEnz2.5.1.115
KEGG Ligand Database for Enzyme Nomenclature2.5.1.115
IUBMB Enzyme Nomenclature2.5.1.115
MEDLINEFind literature relating to 2.5.1.115
MetaCyc2.5.1.115
Rhea expert-curated reactions2.5.1.115
UniProtKB/Swiss-Prot
P73726, HGGT_SYNY3Q8VWJ1, HPT1_ARATHB7FA90, HPT1_ORYSJ
Q0D576, HPT2_ORYSJ

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.5.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.5.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-