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ENZYME

ENZYME entry: EC 2.5.1.116

Accepted Name
homogentisate geranylgeranyltransferase
Alternative Name(s)
HGGT
Reaction catalysed
(2E,6E,10E)-geranylgeranyl diphosphate + H(+) + homogentisate = 6-geranylgeranyl-2-methylbenzene-1,4-diol + CO2 + diphosphate
Comment(s)
  • Involved in the biosynthesis of the vitamin E, tocotrienols.
  • While the enzyme from the bacterium Synechocystis PCC 6803 has higher activity with phytyl diphosphate (EC 2.5.1.115) the enzymes from barley, rice and wheat have only a low activity with that substrate.
Cross-references
BRENDA2.5.1.116
EC2PDB2.5.1.116
ExplorEnz2.5.1.116
PRIAM enzyme-specific profiles2.5.1.116
KEGG Ligand Database for Enzyme Nomenclature2.5.1.116
IUBMB Enzyme Nomenclature2.5.1.116
IntEnz2.5.1.116
MEDLINEFind literature relating to 2.5.1.116
MetaCyc2.5.1.116
Rhea expert-curated reactions2.5.1.116
UniProtKB/Swiss-Prot
Q7XB14, HGGT_HORVUQ0DAK7, HGGT_ORYSJQ7XB13, HGGT_WHEAT

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.5.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.5.-.-
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