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ENZYME

ENZYME entry: EC 2.5.1.124

PURL: https://purl.expasy.org/enzyme/EC/2.5.1.124
Accepted Name
6-linalyl-2-O,3-dimethylflaviolin synthase
Alternative Name(s)
6-(3,7-dimethylocta-1,6-dien-3-yl)-5,7-dihydroxy-2-methoxy-3- methylnaphthalene-1,4-dione synthase
Reaction catalysed
2-O,3-dimethylflaviolin + (2E)-geranyl diphosphate = 6-linalyl-2-O,3-dimethylflaviolin + diphosphate
Comment(s)
  • The enzyme is involved in biosynthesis of the polyketide-isoprenoid furaquinocin D in the bacterium Streptomyces sp. KO-3988.
  • It catalyzes the transfer of a geranyl group to 2-O,3- dimethylflaviolin to yield 6-linalyl-2-O,3-dimethylflaviolin and 7-O- geranyl-2-O,3-dimethylflaviolin (cf. EC 2.5.1.125) in a 10:1 ratio.
Cross-references
BRENDA2.5.1.124
EC2PDB2.5.1.124
ExplorEnz2.5.1.124
KEGG Ligand Database for Enzyme Nomenclature2.5.1.124
IUBMB Enzyme Nomenclature2.5.1.124
MEDLINEFind literature relating to 2.5.1.124
MetaCyc2.5.1.124
Rhea expert-curated reactions2.5.1.124
UniProtKB/Swiss-Prot
Q2L6E3, FUR7_STREO

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