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ENZYME

ENZYME entry: EC 2.5.1.125

Accepted Name
7-geranyloxy-5-hydroxy-2-methoxy-3-methylnaphthalene-1,4-dione synthase
Reaction catalysed
(2E)-geranyl diphosphate + 2-O,3-dimethylflaviolin + H(+) <=> 7-O-geranyl-2-O,3-dimethylflaviolin + diphosphate
Comment(s)
  • The enzyme is involved in furaquinocin biosynthesis in the bacterium Streptomyces sp. KO-3988.
  • It catalyzes the transfer of a geranyl group to 2-O,3- dimethylflaviolin to yield 7-O-geranyl-2-O,3-dimethylflaviolin and 6-linalyl-2-O,3-dimethylflaviolin (cf. EC 2.5.1.124) in a 1:10 ratio.
Cross-references
BRENDA2.5.1.125
EC2PDB2.5.1.125
ExplorEnz2.5.1.125
PRIAM enzyme-specific profiles2.5.1.125
KEGG Ligand Database for Enzyme Nomenclature2.5.1.125
IUBMB Enzyme Nomenclature2.5.1.125
IntEnz2.5.1.125
MEDLINEFind literature relating to 2.5.1.125
MetaCyc2.5.1.125
Rhea expert-curated reactions2.5.1.125
UniProtKB/Swiss-Prot
Q2L6E3, FUR7_STREO

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