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ENZYME

ENZYME entry: EC 2.5.1.16

PURL: https://purl.expasy.org/enzyme/EC/2.5.1.16
Accepted Name
spermidine synthase
Alternative Name(s)
aminopropyltransferase
putrescine aminopropyltransferase
Reaction catalysed
S-adenosyl 3-(methylsulfanyl)propylamine + putrescine = S-methyl-5'-thioadenosine + spermidine + H(+)
Comment(s)
  • The enzymes from the plant Glycine max and from mammalia are highly specific for putrescine as the amine acceptor.
  • The enzymes from the bacteria Escherichia coli and Thermotoga maritima prefer putrescine but are more tolerant toward other amine acceptors, such as spermidine and cadaverine. cf. EC 2.5.1.22 and EC 2.5.1.23.
Cross-references
BRENDA2.5.1.16
EC2PDB2.5.1.16
ExplorEnz2.5.1.16
KEGG Ligand Database for Enzyme Nomenclature2.5.1.16
IUBMB Enzyme Nomenclature2.5.1.16
MEDLINEFind literature relating to 2.5.1.16
MetaCyc2.5.1.16
Rhea expert-curated reactions2.5.1.16
UniProtKB/Swiss-Prot
O82147, SPDE_COFARO48660, SPDE_NICSYQ9ZS45, SPDE_SOLLC
Q9ZUB3, SPDS1_ARATHQ96556, SPDS1_DATSTO48658, SPDS1_HYONI
Q9SMB1, SPDS1_ORYSJQ9ZTR1, SPDS1_PEAO48661, SPDS2_ARATH
Q96557, SPDS2_DATSTO48659, SPDS2_HYONIQ9ZTR0, SPDS2_PEA
O66473, SPEE1_AQUAEQ81JT0, SPEE1_BACANQ814Q1, SPEE1_BACCR
Q8RA94, SPEE1_CALS4Q8EZP1, SPEE1_LEPINQ9X6R0, SPEE1_PSEAE
Q8XQC8, SPEE1_RALN1Q9L091, SPEE1_STRCOO67365, SPEE2_AQUAE
Q81X05, SPEE2_BACANQ815E8, SPEE2_BACCRQ8R977, SPEE2_CALS4
Q8EXA3, SPEE2_LEPINQ9HV34, SPEE2_PSEAEQ8XQC5, SPEE2_RALN1
Q9X8S2, SPEE2_STRCOA3DDA0, SPEE_ACET2Q9YE02, SPEE_AERPE
C4ZDU4, SPEE_AGARVQ0ACK7, SPEE_ALKEHA6TRI3, SPEE_ALKMQ
A8MLM9, SPEE_ALKOOO27950, SPEE_ARCFUQ72X78, SPEE_BACC1
A7GVB2, SPEE_BACCNA9VSG3, SPEE_BACMKP70998, SPEE_BACSU
Q8G4L4, SPEE_BIFLOB8D908, SPEE_BUCA5P57305, SPEE_BUCAI
Q8K9T5, SPEE_BUCAPB8D7B3, SPEE_BUCATB9MRW0, SPEE_CALBD
A4XKM9, SPEE_CALS8Q7NQK7, SPEE_CHRVOA8ALG8, SPEE_CITK8
Q97FX3, SPEE_CLOABA6M1N9, SPEE_CLOB8B2V328, SPEE_CLOBA
B2TMY2, SPEE_CLOBBQ18A85, SPEE_CLOD6B9E5S1, SPEE_CLOK1
A5N219, SPEE_CLOK5Q0TTQ7, SPEE_CLOP1Q8XMY8, SPEE_CLOPE
Q0SVK7, SPEE_CLOPSQ891W4, SPEE_CLOTEQ8FMF7, SPEE_COREF
B1I5Z0, SPEE_DESAPQ9XY92, SPEE_DICDIA7ZHL0, SPEE_ECO24
B7UIG9, SPEE_ECO27B7MBA4, SPEE_ECO45B7LFY8, SPEE_ECO55
P66834, SPEE_ECO57B5YZF6, SPEE_ECO5EB7NI81, SPEE_ECO7I
B7MNY3, SPEE_ECO81B7M162, SPEE_ECO8AC4ZRL4, SPEE_ECOBW
B1XC96, SPEE_ECODHA7ZW70, SPEE_ECOHSA1A7G7, SPEE_ECOK1
Q0TLL3, SPEE_ECOL5P66833, SPEE_ECOL6B1IQL9, SPEE_ECOLC
P09158, SPEE_ECOLIB7N7Z1, SPEE_ECOLUB6HZ96, SPEE_ECOSE
B1LGS2, SPEE_ECOSMQ1RG70, SPEE_ECOUTA4W6M6, SPEE_ENT38
B2VD21, SPEE_ERWT9B7LVY5, SPEE_ESCF3Q9K6B8, SPEE_HALH5
A1WZR2, SPEE_HALHLC4K3X3, SPEE_HAMD5Q17WL9, SPEE_HELAH
B6JM63, SPEE_HELP2B5Z7J7, SPEE_HELPGQ1CT37, SPEE_HELPH
Q9ZL11, SPEE_HELPJB2USZ6, SPEE_HELPSO25503, SPEE_HELPY
P19623, SPEE_HUMANB4U8W2, SPEE_HYDS0B5Y1R1, SPEE_KLEP3
A6T4R6, SPEE_KLEP7B1L5H2, SPEE_KORCOC4Z1Q7, SPEE_LACE2
A9KQ99, SPEE_LACP7B0SI93, SPEE_LEPBAB0STV8, SPEE_LEPBP
Q72V65, SPEE_LEPICQ606H1, SPEE_METCAQ57761, SPEE_METJA
Q2RHH3, SPEE_MOOTAQ64674, SPEE_MOUSEQ7TY95, SPEE_MYCBO
P9WGE4, SPEE_MYCTOP9WGE5, SPEE_MYCTUP60593, SPEE_NEIMA
P60594, SPEE_NEIMBQ9Y8H7, SPEE_NEUCRQ82XD4, SPEE_NITEU
Q3JDL8, SPEE_NITOCQ8CV14, SPEE_OCEIHQ7U3L0, SPEE_PARMW
Q6D1W4, SPEE_PECASC6DC58, SPEE_PECCPQ7N892, SPEE_PHOLL
Q6L1F4, SPEE_PICTOA3PFH4, SPEE_PROM0A2C5F4, SPEE_PROM1
A8G7J0, SPEE_PROM2A2CDX0, SPEE_PROM3A2BZ72, SPEE_PROM5
Q317V6, SPEE_PROM9Q7V9I5, SPEE_PROMAQ7V3X3, SPEE_PROMM
Q7UZI0, SPEE_PROMPA2BTR7, SPEE_PROMSQ46IA2, SPEE_PROMT
Q884N3, SPEE_PSESMQ9V277, SPEE_PYRABA4WHN0, SPEE_PYRAR
A3MU81, SPEE_PYRCJQ8U4G1, SPEE_PYRFUO57950, SPEE_PYRHO
A1RU43, SPEE_PYRILB1YB61, SPEE_PYRNVQ7UWD1, SPEE_RHOBA
Q1GGU4, SPEE_RUESTC3NHE1, SPEE_SACI1C3MQ26, SPEE_SACI2
C3N5P4, SPEE_SACI3C3MVE5, SPEE_SACI4C4KHC0, SPEE_SACI6
C3NEA8, SPEE_SACI7Q9UXE4, SPEE_SACS2B5F815, SPEE_SALA4
A9MPN3, SPEE_SALARQ57T89, SPEE_SALCHB5FIB4, SPEE_SALDC
B5R2R5, SPEE_SALEPB5RHA5, SPEE_SALG2B4TJD2, SPEE_SALHS
B4SU91, SPEE_SALNSQ5PDA0, SPEE_SALPAA9MZR2, SPEE_SALPB
C0Q5M7, SPEE_SALPCB5BL97, SPEE_SALPKB4TXL7, SPEE_SALSV
Q8Z9E2, SPEE_SALTIQ8ZRS3, SPEE_SALTYQ09741, SPEE_SCHPO
A8GJ06, SPEE_SERP5Q8EAX8, SPEE_SHEONB2U2X0, SPEE_SHIB3
Q326B5, SPEE_SHIBSQ32K90, SPEE_SHIDSQ0T879, SPEE_SHIF8
Q83MF0, SPEE_SHIFLQ3Z5N9, SPEE_SHISSQ5WB31, SPEE_SHOC1
Q2NVS1, SPEE_SODGMQ82EU4, SPEE_STRAWB4SM23, SPEE_STRM5
B2FKR1, SPEE_STRMKP66835, SPEE_STRPNP66836, SPEE_STRR6
B9DUY3, SPEE_STRU0Q4JAZ8, SPEE_SULACQ975S5, SPEE_SULTO
Q31QK9, SPEE_SYNE7Q2JQS1, SPEE_SYNJAQ2JQ57, SPEE_SYNJB
Q5N3N4, SPEE_SYNP6Q0I685, SPEE_SYNS3Q9HL75, SPEE_THEAC
Q5JFG9, SPEE_THEKOQ9WZC2, SPEE_THEMAB9KAY3, SPEE_THENN
B6YXJ9, SPEE_THEONA5IJD3, SPEE_THEP1B0K9I5, SPEE_THEP3
B0K172, SPEE_THEPXQ72K55, SPEE_THET2Q97BN7, SPEE_THEVO
B8GQ45, SPEE_THISHQ8D3Q3, SPEE_VIBVUQ7MF74, SPEE_VIBVY
Q7M7Q6, SPEE_WOLSUQ8PFQ4, SPEE_XANACQ4UPN0, SPEE_XANC8
B0RXN7, SPEE_XANCBQ8P447, SPEE_XANCPQ3BN93, SPEE_XANE5
Q2P928, SPEE_XANOMB2SHF6, SPEE_XANOPQ5H6E7, SPEE_XANOR
B2I6M0, SPEE_XYLF2Q9PH03, SPEE_XYLFAB0U1H5, SPEE_XYLFM
Q87F26, SPEE_XYLFTQ12074, SPEE_YEASTA1JJM8, SPEE_YERE8
A7FM33, SPEE_YERP3Q1C3U7, SPEE_YERPAB2K4I2, SPEE_YERPB
Q8ZBJ8, SPEE_YERPEA9R1H4, SPEE_YERPGQ1CLX1, SPEE_YERPN
A4TPU4, SPEE_YERPPQ66EH3, SPEE_YERPSB1JK45, SPEE_YERPY

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All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.5.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.5.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-