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ENZYME

ENZYME entry: EC 2.5.1.16

Accepted Name
spermidine synthase
Alternative Name(s)
aminopropyltransferase
putrescine aminopropyltransferase
Reaction catalysed
putrescine + S-adenosyl 3-(methylsulfanyl)propylamine <=> H(+) + S-methyl-5'-thioadenosine + spermidine
Comment(s)
  • The enzymes from the plant Glycine max and from mammalia are highly specific for putrescine as the amine acceptor.
  • The enzymes from the bacteria Escherichia coli and Thermotoga maritima prefer putrescine but are more tolerant toward other amine acceptors, such as spermidine and cadaverine. cf. EC 2.5.1.22 and EC 2.5.1.23.
Cross-references
BRENDA2.5.1.16
EC2PDB2.5.1.16
ExplorEnz2.5.1.16
PRIAM enzyme-specific profiles2.5.1.16
KEGG Ligand Database for Enzyme Nomenclature2.5.1.16
IUBMB Enzyme Nomenclature2.5.1.16
IntEnz2.5.1.16
MEDLINEFind literature relating to 2.5.1.16
MetaCyc2.5.1.16
Rhea expert-curated reactions2.5.1.16
UniProtKB/Swiss-Prot
O82147, SPDE_COFARO48660, SPDE_NICSYQ9ZS45, SPDE_SOLLC
Q9ZUB3, SPDS1_ARATHQ96556, SPDS1_DATSTO48658, SPDS1_HYONI
Q9SMB1, SPDS1_ORYSJQ9ZTR1, SPDS1_PEAO48661, SPDS2_ARATH
Q96557, SPDS2_DATSTO48659, SPDS2_HYONIQ9ZTR0, SPDS2_PEA
O66473, SPEE1_AQUAEQ81JT0, SPEE1_BACANQ814Q1, SPEE1_BACCR
Q8RA94, SPEE1_CALS4Q8EZP1, SPEE1_LEPINQ9X6R0, SPEE1_PSEAE
Q8XQC8, SPEE1_RALSOQ9L091, SPEE1_STRCOO67365, SPEE2_AQUAE
Q81X05, SPEE2_BACANQ815E8, SPEE2_BACCRQ8R977, SPEE2_CALS4
Q8EXA3, SPEE2_LEPINQ9HV34, SPEE2_PSEAEQ8XQC5, SPEE2_RALSO
Q9X8S2, SPEE2_STRCOA3DDA0, SPEE_ACET2Q9YE02, SPEE_AERPE
C4ZDU4, SPEE_AGARVQ5WB31, SPEE_ALKCKQ0ACK7, SPEE_ALKEH
A6TRI3, SPEE_ALKMQA8MLM9, SPEE_ALKOOO27950, SPEE_ARCFU
Q72X78, SPEE_BACC1A7GVB2, SPEE_BACCNA9VSG3, SPEE_BACMK
P70998, SPEE_BACSUQ8G4L4, SPEE_BIFLOB8D908, SPEE_BUCA5
P57305, SPEE_BUCAIQ8K9T5, SPEE_BUCAPB8D7B3, SPEE_BUCAT
B9MRW0, SPEE_CALBDA4XKM9, SPEE_CALS8Q7NQK7, SPEE_CHRVO
A8ALG8, SPEE_CITK8Q97FX3, SPEE_CLOABA6M1N9, SPEE_CLOB8
B2V328, SPEE_CLOBAB2TMY2, SPEE_CLOBBQ18A85, SPEE_CLOD6
B9E5S1, SPEE_CLOK1A5N219, SPEE_CLOK5Q0TTQ7, SPEE_CLOP1
Q8XMY8, SPEE_CLOPEQ0SVK7, SPEE_CLOPSQ891W4, SPEE_CLOTE
Q8FMF7, SPEE_COREFB1I5Z0, SPEE_DESAPQ9XY92, SPEE_DICDI
A7ZHL0, SPEE_ECO24B7UIG9, SPEE_ECO27B7MBA4, SPEE_ECO45
B7LFY8, SPEE_ECO55P66834, SPEE_ECO57B5YZF6, SPEE_ECO5E
B7NI81, SPEE_ECO7IB7MNY3, SPEE_ECO81B7M162, SPEE_ECO8A
C4ZRL4, SPEE_ECOBWB1XC96, SPEE_ECODHA7ZW70, SPEE_ECOHS
A1A7G7, SPEE_ECOK1Q0TLL3, SPEE_ECOL5P66833, SPEE_ECOL6
B1IQL9, SPEE_ECOLCP09158, SPEE_ECOLIB7N7Z1, SPEE_ECOLU
B6HZ96, SPEE_ECOSEB1LGS2, SPEE_ECOSMQ1RG70, SPEE_ECOUT
A4W6M6, SPEE_ENT38B2VD21, SPEE_ERWT9B7LVY5, SPEE_ESCF3
Q9K6B8, SPEE_HALH5A1WZR2, SPEE_HALHLC4K3X3, SPEE_HAMD5
Q17WL9, SPEE_HELAHB6JM63, SPEE_HELP2B5Z7J7, SPEE_HELPG
Q1CT37, SPEE_HELPHQ9ZL11, SPEE_HELPJB2USZ6, SPEE_HELPS
O25503, SPEE_HELPYP19623, SPEE_HUMANB4U8W2, SPEE_HYDS0
B5Y1R1, SPEE_KLEP3A6T4R6, SPEE_KLEP7B1L5H2, SPEE_KORCO
C4Z1Q7, SPEE_LACE2A9KQ99, SPEE_LACP7B0SI93, SPEE_LEPBA
B0STV8, SPEE_LEPBPQ72V65, SPEE_LEPICQ606H1, SPEE_METCA
Q57761, SPEE_METJAQ2RHH3, SPEE_MOOTAQ64674, SPEE_MOUSE
Q7TY95, SPEE_MYCBOP9WGE4, SPEE_MYCTOP9WGE5, SPEE_MYCTU
P60593, SPEE_NEIMAP60594, SPEE_NEIMBQ9Y8H7, SPEE_NEUCR
Q82XD4, SPEE_NITEUQ3JDL8, SPEE_NITOCQ8CV14, SPEE_OCEIH
Q7U3L0, SPEE_PARMWQ6D1W4, SPEE_PECASC6DC58, SPEE_PECCP
Q7N892, SPEE_PHOLLQ6L1F4, SPEE_PICTOA3PFH4, SPEE_PROM0
A2C5F4, SPEE_PROM1A8G7J0, SPEE_PROM2A2CDX0, SPEE_PROM3
A2BZ72, SPEE_PROM5Q317V6, SPEE_PROM9Q7V9I5, SPEE_PROMA
Q7V3X3, SPEE_PROMMQ7UZI0, SPEE_PROMPA2BTR7, SPEE_PROMS
Q46IA2, SPEE_PROMTQ884N3, SPEE_PSESMQ9V277, SPEE_PYRAB
A4WHN0, SPEE_PYRARA3MU81, SPEE_PYRCJQ8U4G1, SPEE_PYRFU
O57950, SPEE_PYRHOA1RU43, SPEE_PYRILB1YB61, SPEE_PYRNV
Q7UWD1, SPEE_RHOBAQ1GGU4, SPEE_RUESTQ9UXE4, SPEE_SACS2
B5F815, SPEE_SALA4A9MPN3, SPEE_SALARQ57T89, SPEE_SALCH
B5FIB4, SPEE_SALDCB5R2R5, SPEE_SALEPB5RHA5, SPEE_SALG2
B4TJD2, SPEE_SALHSB4SU91, SPEE_SALNSQ5PDA0, SPEE_SALPA
A9MZR2, SPEE_SALPBC0Q5M7, SPEE_SALPCB5BL97, SPEE_SALPK
B4TXL7, SPEE_SALSVQ8Z9E2, SPEE_SALTIQ8ZRS3, SPEE_SALTY
Q09741, SPEE_SCHPOA8GJ06, SPEE_SERP5Q8EAX8, SPEE_SHEON
B2U2X0, SPEE_SHIB3Q326B5, SPEE_SHIBSQ32K90, SPEE_SHIDS
Q0T879, SPEE_SHIF8Q83MF0, SPEE_SHIFLQ3Z5N9, SPEE_SHISS
Q2NVS1, SPEE_SODGMQ82EU4, SPEE_STRAWB4SM23, SPEE_STRM5
B2FKR1, SPEE_STRMKP66835, SPEE_STRPNP66836, SPEE_STRR6
B9DUY3, SPEE_STRU0Q4JAZ8, SPEE_SULACC3N5P4, SPEE_SULIA
C4KHC0, SPEE_SULIKC3MQ26, SPEE_SULILC3MVE5, SPEE_SULIM
C3NHE1, SPEE_SULINC3NEA8, SPEE_SULIYQ975S5, SPEE_SULTO
Q31QK9, SPEE_SYNE7Q2JQS1, SPEE_SYNJAQ2JQ57, SPEE_SYNJB
Q5N3N4, SPEE_SYNP6Q0I685, SPEE_SYNS3Q9HL75, SPEE_THEAC
Q5JFG9, SPEE_THEKOQ9WZC2, SPEE_THEMAB9KAY3, SPEE_THENN
B6YXJ9, SPEE_THEONA5IJD3, SPEE_THEP1B0K9I5, SPEE_THEP3
B0K172, SPEE_THEPXQ72K55, SPEE_THET2Q97BN7, SPEE_THEVO
B8GQ45, SPEE_THISHQ8D3Q3, SPEE_VIBVUQ7MF74, SPEE_VIBVY
Q7M7Q6, SPEE_WOLSUQ8PFQ4, SPEE_XANACQ3BN93, SPEE_XANC5
Q4UPN0, SPEE_XANC8B0RXN7, SPEE_XANCBQ8P447, SPEE_XANCP
Q2P928, SPEE_XANOMB2SHF6, SPEE_XANOPQ5H6E7, SPEE_XANOR
B2I6M0, SPEE_XYLF2Q9PH03, SPEE_XYLFAB0U1H5, SPEE_XYLFM
Q87F26, SPEE_XYLFTQ12074, SPEE_YEASTA1JJM8, SPEE_YERE8
A7FM33, SPEE_YERP3Q1C3U7, SPEE_YERPAB2K4I2, SPEE_YERPB
Q8ZBJ8, SPEE_YERPEA9R1H4, SPEE_YERPGQ1CLX1, SPEE_YERPN
A4TPU4, SPEE_YERPPQ66EH3, SPEE_YERPSB1JK45, SPEE_YERPY

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All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.5.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.5.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-