A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.

ENZYME entry: EC 2.5.1.22

Accepted Name
Spermine synthase.
Alternative Name(s)
Spermidine aminopropyltransferase.
Reaction catalysed
S-adenosyl 3-(methylthio)propylamine + spermidine <=> S-methyl-5'-thioadenosine + spermine
Comment(s)
The enzyme from mammalia is highly specific for spermidine, cf. EC 2.5.1.16 and EC 2.5.1.23.
Cross-references
PROSITEPDOC01033
BRENDA2.5.1.22
EC2PDB2.5.1.22
ExplorEnz2.5.1.22
PRIAM enzyme-specific profiles2.5.1.22
KEGG Ligand Database for Enzyme Nomenclature2.5.1.22
IUBMB Enzyme Nomenclature2.5.1.22
IntEnz2.5.1.22
MEDLINEFind literature relating to 2.5.1.22
MetaCyc2.5.1.22
UniProtKB/Swiss-Prot
P09158, SPEE_ECOLI;  Q5SK28, SPEE_THET8;  Q94BN2, SPSY_ARATH;  
Q3SZA5, SPSY_BOVIN;  P52788, SPSY_HUMAN;  P97355, SPSY_MOUSE;  
Q12455, SPSY_YEAST;  

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All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.5.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.5.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-