Home  |  Contact

ENZYME entry: EC 2.6.1.114

Accepted Name
8-demethyl-8-aminoriboflavin-5'-phosphate synthase.
Reaction catalysed
L-glutamate + FMN + O(2) + H(2)O + 3 acceptor <=> 2-oxoglutarate + 8-amino-8-demethylriboflavin 5'-phosphate + CO(2) + 3 reduced acceptor
Comment(s)
  • The enzyme, characterized from the bacterium Streptomyces davawensis, has the activities of an oxidoreductase, a decarboxylase, and an aminotransferase.
  • Its combined actions result in the replacement of a methyl substituent of one of the aromatic rings of FMN by an amino group, a step in the biosynthetic pathway of roseoflavin.
  • The reaction requires thiamine for completion.
Cross-references
BRENDA2.6.1.114
EC2PDB2.6.1.114
ExplorEnz2.6.1.114
PRIAM enzyme-specific profiles2.6.1.114
KEGG Ligand Database for Enzyme Nomenclature2.6.1.114
IUBMB Enzyme Nomenclature2.6.1.114
IntEnz2.6.1.114
MEDLINEFind literature relating to 2.6.1.114
MetaCyc2.6.1.114
UniProtKB/Swiss-Prot
K4REZ6, ROSB_STRDJ

View entry in original ENZYME format
View entry in raw text format (no links)
All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.6.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.6.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-