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ENZYME entry: EC 2.6.1.23

Accepted Name
4-hydroxyglutamate transaminase.
Alternative Name(s)
4-hydroxyglutamate aminotransferase.
Reaction catalysed
Erythro-4-hydroxy-L-glutamate + 2-oxoglutarate <=> (4R)-4-hydroxy-2-oxoglutarate + L-glutamate
Comment(s)
  • The enzyme participates in a degradation pathway of trans-4-hydroxy- L-proline, a compound that contributes to the stability of the collagen triple helix.
  • Oxaloacetate can replace 2-oxoglutarate.
  • This enzyme may be identical with EC 2.6.1.1.
Cross-references
BRENDA2.6.1.23
EC2PDB2.6.1.23
ExplorEnz2.6.1.23
PRIAM enzyme-specific profiles2.6.1.23
KEGG Ligand Database for Enzyme Nomenclature2.6.1.23
IUBMB Enzyme Nomenclature2.6.1.23
IntEnz2.6.1.23
MEDLINEFind literature relating to 2.6.1.23
MetaCyc2.6.1.23
Rhea expert-curated reactions2.6.1.23

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.6.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.6.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-