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A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.

ENZYME entry: EC 2.6.1.5

Accepted Name
Tyrosine transaminase.
Alternative Name(s)
TyrAT.
Tyrosine aminotransferase.
Reaction catalysed
L-tyrosine + 2-oxoglutarate <=> 4-hydroxyphenylpyruvate + L-glutamate
Cofactor(s)
Pyridoxal 5'-phosphate.
Comment(s)
  • L-phenylalanine can act instead of L-tyrosine.
  • The mitochondrial enzyme may be identical with EC 2.6.1.1.
  • The three isoenzymic forms are interconverted by EC 3.4.22.32 and EC 3.4.22.33.
  • The enzyme can also catalyze the final step in the methionine-salvage pathway of Klebsiella pneumoniae.
Cross-references
PROSITEPDOC00098
BRENDA2.6.1.5
EC2PDB2.6.1.5
ExplorEnz2.6.1.5
PRIAM enzyme-specific profiles2.6.1.5
KEGG Ligand Database for Enzyme Nomenclature2.6.1.5
IUBMB Enzyme Nomenclature2.6.1.5
IntEnz2.6.1.5
MEDLINEFind literature relating to 2.6.1.5
MetaCyc2.6.1.5
UniProtKB/Swiss-Prot
F8P1W6, AMT1_SERL9;  B7STY2, ATRD_TAPPA;  Q58CZ9, ATTY_BOVIN;  
Q54K95, ATTY_DICDI;  P17735, ATTY_HUMAN;  Q8QZR1, ATTY_MOUSE;  
P04694, ATTY_RAT;  Q02636, ATTY_RHIME;  P33447, ATTY_TRYCR;  
Q9C969, ISS1_ARATH;  Q9LVY1, TAT_ARATH;  O85746, TYRB_KLEPN;  

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All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.6.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.6.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-