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ENZYME entry: EC 2.6.1.96

Accepted Name
4-aminobutyrate--pyruvate transaminase.
Alternative Name(s)
4-aminobutyrate aminotransferase.
GABA transaminase.
Gamma-aminobutyrate aminotransaminase.
Gamma-aminobutyric acid pyruvate transaminase.
Reaction catalysed
  • 4-aminobutanoate + pyruvate <=> succinate semialdehyde + L-alanine
  • 4-aminobutanoate + glyoxylate <=> succinate semialdehyde + glycine
Cofactor(s)
Pyridoxal 5'-phosphate.
Comment(s)
  • The enzyme is found in plants that do not have the 2-oxoglutarate dependent enzyme (cf. EC 2.6.1.19).
  • The reaction with pyruvate is reversible while the reaction with glyoxylate only takes place in the forward direction.
Cross-references
BRENDA2.6.1.96
EC2PDB2.6.1.96
ExplorEnz2.6.1.96
PRIAM enzyme-specific profiles2.6.1.96
KEGG Ligand Database for Enzyme Nomenclature2.6.1.96
IUBMB Enzyme Nomenclature2.6.1.96
IntEnz2.6.1.96
MEDLINEFind literature relating to 2.6.1.96
MetaCyc2.6.1.96
Rhea expert-curated reactions2.6.1.96
UniProtKB/Swiss-Prot
Q01K11, GATP1_ORYSI;  Q7XN11, GATP1_ORYSJ;  Q84P54, GATP1_SOLLC;  
Q01K12, GATP2_ORYSI;  Q7XN12, GATP2_ORYSJ;  Q84P53, GATP2_SOLLC;  
B8BBZ7, GATP3_ORYSI;  Q6ZCF0, GATP3_ORYSJ;  Q84P52, GATP3_SOLLC;  
Q6ZH29, GATP4_ORYSJ;  Q94CE5, GATP_ARATH;  

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.6.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.6.-.-
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