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ENZYME

ENZYME entry: EC 2.7.1.167

Accepted Name
D-glycero-beta-D-manno-heptose-7-phosphate kinase
Alternative Name(s)
D-beta-D-heptose-7-phosphate kinase
D-beta-D-heptose 7-phosphate kinase/D-beta-D-heptose 1-phosphate adenylyltransferase
D-beta-D-heptose 7-phosphotransferase
glycero-manno-heptose 7-phosphate kinase
heptose 7-phosphate kinase
HldE1 heptokinase
Reaction catalysed
ATP + D-glycero-beta-D-manno-heptose 7-phosphate <=> ADP + D-glycero-beta-D-manno-heptose 1,7-bisphosphate + H(+)
Comment(s)
  • The bifunctional protein hldE includes D-glycero-beta-D-manno- heptose-7-phosphate kinase and D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase activity (cf. EC 2.7.7.70).
  • The enzyme is involved in biosynthesis of ADP-L-glycero-beta-D-manno- heptose, which is utilized for assembly of the lipopolysaccharide inner core in Gram-negative bacteria.
  • The enzyme selectively produces D-glycero-beta-D-manno-heptose 1,7- bisphosphate.
Cross-references
BRENDA2.7.1.167
EC2PDB2.7.1.167
ExplorEnz2.7.1.167
PRIAM enzyme-specific profiles2.7.1.167
KEGG Ligand Database for Enzyme Nomenclature2.7.1.167
IUBMB Enzyme Nomenclature2.7.1.167
IntEnz2.7.1.167
MEDLINEFind literature relating to 2.7.1.167
MetaCyc2.7.1.167
Rhea expert-curated reactions2.7.1.167
UniProtKB/Swiss-Prot
Q7WGU8, HEPPK_BORBRA5FVE7, HLDE_ACICJA3MZC0, HLDE_ACTP2
Q8GLU7, HLDE_ACTPLA6VP06, HLDE_ACTSZA0KPL4, HLDE_AERHH
A4SIG6, HLDE_AERS4Q0VM60, HLDE_ALCBSA8EVR4, HLDE_ALIB4
Q5E2L7, HLDE_ALIF1B5FB67, HLDE_ALIFMB6ELZ7, HLDE_ALISL
Q0A4T7, HLDE_ALKEHA8I5B0, HLDE_AZOC5C1DGT9, HLDE_AZOVD
Q7VQQ6, HLDE_BLOFLQ493X3, HLDE_BLOPBQ89HR3, HLDE_BRADU
A5EN78, HLDE_BRASBA4YYB6, HLDE_BRASOA7ZE26, HLDE_CAMC1
A7GZF6, HLDE_CAMC5A0RQR9, HLDE_CAMFFA8FMK8, HLDE_CAMJ8
A7H2L7, HLDE_CAMJDQ6TG09, HLDE_CAMJEA1W0D6, HLDE_CAMJJ
Q5HTW1, HLDE_CAMJRB0T663, HLDE_CAUSKQ9A2C5, HLDE_CAUVC
Q1R1M6, HLDE_CHRSDB5EEZ1, HLDE_CITBBA8APT1, HLDE_CITK8
A9KDJ2, HLDE_COXBNA9N9S2, HLDE_COXBRQ83B60, HLDE_COXBU
A7MP93, HLDE_CROS8B8FB71, HLDE_DESALA5EWS4, HLDE_DICNV
A7ZRT3, HLDE_ECO24B7UIW0, HLDE_ECO27B7MAC8, HLDE_ECO45
B7LGY7, HLDE_ECO55Q7AAQ7, HLDE_ECO57B5YR91, HLDE_ECO5E
B7NJR5, HLDE_ECO7IB7N0K1, HLDE_ECO81B7LZK1, HLDE_ECO8A
C4ZQW9, HLDE_ECOBWB1XG57, HLDE_ECODHA8A4K6, HLDE_ECOHS
A1AFX4, HLDE_ECOK1Q0TD55, HLDE_ECOL5Q8FDH5, HLDE_ECOL6
B1IRR4, HLDE_ECOLCP76658, HLDE_ECOLIB7ND40, HLDE_ECOLU
B6I423, HLDE_ECOSEB1LF43, HLDE_ECOSMQ1R6S9, HLDE_ECOUT
C5BHH2, HLDE_EDWI9A4WEI4, HLDE_ENT38B2VGJ9, HLDE_ERWT9
B7LQC9, HLDE_ESCF3Q39X60, HLDE_GEOMGQ74BF6, HLDE_GEOSL
A5G6F4, HLDE_GEOURA9HDB1, HLDE_GLUDAQ5FS52, HLDE_GLUOX
Q0BUU1, HLDE_GRABCQ7VM30, HLDE_HAEDUQ4QKN8, HLDE_HAEI8
A5UCC3, HLDE_HAEIEA5UEH8, HLDE_HAEIGO05074, HLDE_HAEIN
Q0I1X5, HLDE_HAES1Q2SN34, HLDE_HAHCHA1WZB3, HLDE_HALHL
Q17WK1, HLDE_HELAHQ7VFZ3, HLDE_HELHPB6JM82, HLDE_HELP2
B5Z7L8, HLDE_HELPGQ1CT14, HLDE_HELPHQ9ZKZ0, HLDE_HELPJ
B2USX2, HLDE_HELPSO25529, HLDE_HELPYQ31IC2, HLDE_HYDCU
Q0C190, HLDE_HYPNAB5XU40, HLDE_KLEP3A6TE31, HLDE_KLEP7
Q1IJZ0, HLDE_KORVEA0L7X0, HLDE_MAGMMQ2W993, HLDE_MAGSA
Q65T41, HLDE_MANSMA6W0Z9, HLDE_MARMSA1TYR4, HLDE_MARN8
Q607M3, HLDE_METCAQ1H3A0, HLDE_METFKQ1QNS3, HLDE_NITHX
Q3J7Y0, HLDE_NITOCA6Q4Z6, HLDE_NITSBQ3STQ8, HLDE_NITWN
A7HUC7, HLDE_PARL1Q9CME6, HLDE_PASMUQ6D164, HLDE_PECAS
C6DDL3, HLDE_PECCPA1AV12, HLDE_PELPDQ7N0C3, HLDE_PHOLL
Q6LUZ5, HLDE_PHOPRB4EW46, HLDE_PROMHQ48P39, HLDE_PSE14
A6VDB5, HLDE_PSEA7B7V388, HLDE_PSEA8Q02F21, HLDE_PSEAB
Q9HUG9, HLDE_PSEAEQ1I411, HLDE_PSEE4Q4KJA9, HLDE_PSEF5
C3KDB8, HLDE_PSEFSA4XPU9, HLDE_PSEMYA5W9W6, HLDE_PSEP1
Q3KJ28, HLDE_PSEPFB0KL32, HLDE_PSEPGQ88D93, HLDE_PSEPK
B1J331, HLDE_PSEPWQ87VF4, HLDE_PSESMQ3IHX7, HLDE_PSET1
Q4ZZ15, HLDE_PSEU2A1SZY2, HLDE_PSYINQ98I54, HLDE_RHILO
Q2IZP7, HLDE_RHOP2Q07RN1, HLDE_RHOP5Q6N2R5, HLDE_RHOPA
Q219E2, HLDE_RHOPBQ13AN7, HLDE_RHOPSB3QJ47, HLDE_RHOPT
Q2RY67, HLDE_RHORTB5F696, HLDE_SALA4A9MPW3, HLDE_SALAR
Q57JQ9, HLDE_SALCHB5FHT5, HLDE_SALDCB5QZ36, HLDE_SALEP
B5REF8, HLDE_SALG2B4TI51, HLDE_SALHSB4T670, HLDE_SALNS
Q5PC86, HLDE_SALPAA9N5X8, HLDE_SALPBC0PYX3, HLDE_SALPC
B5BG11, HLDE_SALPKB4TVT4, HLDE_SALSVQ8XEW9, HLDE_SALTI
Q7CPR9, HLDE_SALTYA8GJU3, HLDE_SERP5A1S3I3, HLDE_SHEAM
B8EE43, HLDE_SHEB2A3D837, HLDE_SHEB5A6WJS7, HLDE_SHEB8
A9L2P0, HLDE_SHEB9Q12RC7, HLDE_SHEDOQ07Y78, HLDE_SHEFN
B0TTF2, HLDE_SHEHHA3QAN3, HLDE_SHELPQ8EAZ2, HLDE_SHEON
A8H086, HLDE_SHEPAA4Y9Z9, HLDE_SHEPCB8CVJ1, HLDE_SHEPW
A0KTG8, HLDE_SHESAA8FZZ3, HLDE_SHESHQ0HFL0, HLDE_SHESM
Q0HYC0, HLDE_SHESRA1RGD1, HLDE_SHESWB2U1F7, HLDE_SHIB3
Q31WY3, HLDE_SHIBSQ32BR2, HLDE_SHIDSQ0T0L1, HLDE_SHIF8
Q7UBI8, HLDE_SHIFLQ3YXJ0, HLDE_SHISSQ2NWD9, HLDE_SODGM
Q9Z5B5, HLDE_STRCOA4VR47, HLDE_STUS1Q30T22, HLDE_SULDN
Q3A526, HLDE_SYNC1B3E5M9, HLDE_TRIL1B7VIX1, HLDE_VIBA3
A7MWN3, HLDE_VIBC1A5F5J2, HLDE_VIBC3C3LQY0, HLDE_VIBCM
Q87SJ9, HLDE_VIBPAQ8DEH7, HLDE_VIBVUQ7MNY3, HLDE_VIBVY
Q7M9U1, HLDE_WOLSUA1JQV6, HLDE_YERE8A7FE79, HLDE_YERP3
Q1C374, HLDE_YERPAB2K2H4, HLDE_YERPBQ8ZI60, HLDE_YERPE
A9R7D5, HLDE_YERPGQ1CMD4, HLDE_YERPNA4THT9, HLDE_YERPP
Q665V3, HLDE_YERPSB1JM26, HLDE_YERPY

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.7.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.7.-.-
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