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ENZYME

ENZYME entry: EC 2.7.7.70

Accepted Name
D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase
Alternative Name(s)
D-glycero-D-manno-heptose-1beta-phosphate adenylyltransferase
Reaction catalysed
ATP + D-glycero-beta-D-manno-heptose 1-phosphate + H(+) <=> ADP-D-glycero-beta-D-manno-heptose + diphosphate
Comment(s)
  • The bifunctional protein hldE includes D-glycero-beta-D-manno- heptose-7-phosphate kinase and D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase activity (cf. EC 2.7.1.167).
  • The enzyme is involved in biosynthesis of ADP-L-glycero-beta-D-manno- heptose, which is utilized for assembly of the lipopolysaccharide inner core in Gram-negative bacteria.
Cross-references
BRENDA2.7.7.70
EC2PDB2.7.7.70
ExplorEnz2.7.7.70
PRIAM enzyme-specific profiles2.7.7.70
KEGG Ligand Database for Enzyme Nomenclature2.7.7.70
IUBMB Enzyme Nomenclature2.7.7.70
IntEnz2.7.7.70
MEDLINEFind literature relating to 2.7.7.70
MetaCyc2.7.7.70
Rhea expert-curated reactions2.7.7.70
UniProtKB/Swiss-Prot
Q7WF17, HEPPA_BORBRA5FVE7, HLDE_ACICJA3MZC0, HLDE_ACTP2
Q8GLU7, HLDE_ACTPLA6VP06, HLDE_ACTSZA0KPL4, HLDE_AERHH
A4SIG6, HLDE_AERS4Q0VM60, HLDE_ALCBSA8EVR4, HLDE_ALIB4
Q5E2L7, HLDE_ALIF1B5FB67, HLDE_ALIFMB6ELZ7, HLDE_ALISL
Q0A4T7, HLDE_ALKEHA8I5B0, HLDE_AZOC5C1DGT9, HLDE_AZOVD
Q7VQQ6, HLDE_BLOFLQ493X3, HLDE_BLOPBQ89HR3, HLDE_BRADU
A5EN78, HLDE_BRASBA4YYB6, HLDE_BRASOA7ZE26, HLDE_CAMC1
A7GZF6, HLDE_CAMC5A0RQR9, HLDE_CAMFFA8FMK8, HLDE_CAMJ8
A7H2L7, HLDE_CAMJDQ6TG09, HLDE_CAMJEA1W0D6, HLDE_CAMJJ
Q5HTW1, HLDE_CAMJRB0T663, HLDE_CAUSKQ9A2C5, HLDE_CAUVC
Q1R1M6, HLDE_CHRSDB5EEZ1, HLDE_CITBBA8APT1, HLDE_CITK8
A9KDJ2, HLDE_COXBNA9N9S2, HLDE_COXBRQ83B60, HLDE_COXBU
A7MP93, HLDE_CROS8B8FB71, HLDE_DESALA5EWS4, HLDE_DICNV
A7ZRT3, HLDE_ECO24B7UIW0, HLDE_ECO27B7MAC8, HLDE_ECO45
B7LGY7, HLDE_ECO55Q7AAQ7, HLDE_ECO57B5YR91, HLDE_ECO5E
B7NJR5, HLDE_ECO7IB7N0K1, HLDE_ECO81B7LZK1, HLDE_ECO8A
C4ZQW9, HLDE_ECOBWB1XG57, HLDE_ECODHA8A4K6, HLDE_ECOHS
A1AFX4, HLDE_ECOK1Q0TD55, HLDE_ECOL5Q8FDH5, HLDE_ECOL6
B1IRR4, HLDE_ECOLCP76658, HLDE_ECOLIB7ND40, HLDE_ECOLU
B6I423, HLDE_ECOSEB1LF43, HLDE_ECOSMQ1R6S9, HLDE_ECOUT
C5BHH2, HLDE_EDWI9A4WEI4, HLDE_ENT38B2VGJ9, HLDE_ERWT9
B7LQC9, HLDE_ESCF3Q39X60, HLDE_GEOMGQ74BF6, HLDE_GEOSL
A5G6F4, HLDE_GEOURA9HDB1, HLDE_GLUDAQ5FS52, HLDE_GLUOX
Q0BUU1, HLDE_GRABCQ7VM30, HLDE_HAEDUQ4QKN8, HLDE_HAEI8
A5UCC3, HLDE_HAEIEA5UEH8, HLDE_HAEIGO05074, HLDE_HAEIN
Q0I1X5, HLDE_HAES1Q2SN34, HLDE_HAHCHA1WZB3, HLDE_HALHL
Q17WK1, HLDE_HELAHQ7VFZ3, HLDE_HELHPB6JM82, HLDE_HELP2
B5Z7L8, HLDE_HELPGQ1CT14, HLDE_HELPHQ9ZKZ0, HLDE_HELPJ
B2USX2, HLDE_HELPSO25529, HLDE_HELPYQ31IC2, HLDE_HYDCU
Q0C190, HLDE_HYPNAB5XU40, HLDE_KLEP3A6TE31, HLDE_KLEP7
Q1IJZ0, HLDE_KORVEA0L7X0, HLDE_MAGMMQ2W993, HLDE_MAGSA
Q65T41, HLDE_MANSMA6W0Z9, HLDE_MARMSA1TYR4, HLDE_MARN8
Q607M3, HLDE_METCAQ1H3A0, HLDE_METFKQ1QNS3, HLDE_NITHX
Q3J7Y0, HLDE_NITOCA6Q4Z6, HLDE_NITSBQ3STQ8, HLDE_NITWN
A7HUC7, HLDE_PARL1Q9CME6, HLDE_PASMUQ6D164, HLDE_PECAS
C6DDL3, HLDE_PECCPA1AV12, HLDE_PELPDQ7N0C3, HLDE_PHOLL
Q6LUZ5, HLDE_PHOPRB4EW46, HLDE_PROMHQ48P39, HLDE_PSE14
A6VDB5, HLDE_PSEA7B7V388, HLDE_PSEA8Q02F21, HLDE_PSEAB
Q9HUG9, HLDE_PSEAEQ1I411, HLDE_PSEE4Q4KJA9, HLDE_PSEF5
C3KDB8, HLDE_PSEFSA4XPU9, HLDE_PSEMYA5W9W6, HLDE_PSEP1
Q3KJ28, HLDE_PSEPFB0KL32, HLDE_PSEPGQ88D93, HLDE_PSEPK
B1J331, HLDE_PSEPWQ87VF4, HLDE_PSESMQ3IHX7, HLDE_PSET1
Q4ZZ15, HLDE_PSEU2A4VR47, HLDE_PSEU5A1SZY2, HLDE_PSYIN
Q98I54, HLDE_RHILOQ2IZP7, HLDE_RHOP2Q07RN1, HLDE_RHOP5
Q6N2R5, HLDE_RHOPAQ219E2, HLDE_RHOPBQ13AN7, HLDE_RHOPS
B3QJ47, HLDE_RHOPTQ2RY67, HLDE_RHORTB5F696, HLDE_SALA4
A9MPW3, HLDE_SALARQ57JQ9, HLDE_SALCHB5FHT5, HLDE_SALDC
B5QZ36, HLDE_SALEPB5REF8, HLDE_SALG2B4TI51, HLDE_SALHS
B4T670, HLDE_SALNSQ5PC86, HLDE_SALPAA9N5X8, HLDE_SALPB
C0PYX3, HLDE_SALPCB5BG11, HLDE_SALPKB4TVT4, HLDE_SALSV
Q8XEW9, HLDE_SALTIQ7CPR9, HLDE_SALTYA8GJU3, HLDE_SERP5
A1S3I3, HLDE_SHEAMB8EE43, HLDE_SHEB2A3D837, HLDE_SHEB5
A6WJS7, HLDE_SHEB8A9L2P0, HLDE_SHEB9Q12RC7, HLDE_SHEDO
Q07Y78, HLDE_SHEFNB0TTF2, HLDE_SHEHHA3QAN3, HLDE_SHELP
Q8EAZ2, HLDE_SHEONA8H086, HLDE_SHEPAA4Y9Z9, HLDE_SHEPC
B8CVJ1, HLDE_SHEPWA0KTG8, HLDE_SHESAA8FZZ3, HLDE_SHESH
Q0HFL0, HLDE_SHESMQ0HYC0, HLDE_SHESRA1RGD1, HLDE_SHESW
B2U1F7, HLDE_SHIB3Q31WY3, HLDE_SHIBSQ32BR2, HLDE_SHIDS
Q0T0L1, HLDE_SHIF8Q7UBI8, HLDE_SHIFLQ3YXJ0, HLDE_SHISS
Q2NWD9, HLDE_SODGMQ9Z5B5, HLDE_STRCOQ30T22, HLDE_SULDN
Q3A526, HLDE_SYNC1B3E5M9, HLDE_TRIL1B7VIX1, HLDE_VIBA3
A7MWN3, HLDE_VIBC1A5F5J2, HLDE_VIBC3C3LQY0, HLDE_VIBCM
Q87SJ9, HLDE_VIBPAQ8DEH7, HLDE_VIBVUQ7MNY3, HLDE_VIBVY
Q7M9U1, HLDE_WOLSUA1JQV6, HLDE_YERE8A7FE79, HLDE_YERP3
Q1C374, HLDE_YERPAB2K2H4, HLDE_YERPBQ8ZI60, HLDE_YERPE
A9R7D5, HLDE_YERPGQ1CMD4, HLDE_YERPNA4THT9, HLDE_YERPP
Q665V3, HLDE_YERPSB1JM26, HLDE_YERPY

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.7.7.-
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