ENZYME entry: EC 184.108.40.206
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|Mannose PTS permease.|
|[Protein]-N(pi)-phospho-L-histidine + D-mannose(Side 1) <=> [protein]-L-histidine + D-mannose 6-phosphate(Side 2)|
- This enzyme is a component (known as enzyme II) of a
phosphoenolpyruvate (PEP)-dependent, sugar transporting
phosphotransferase system (PTS).
- The system, which is found only in prokaryotes, simultaneously
transports its substrate from the periplasm or extracellular space
into the cytoplasm and phosphorylates it.
- The phosphate donor, which is shared among the different systems,
is a phospho-carrier protein of low molecular mass that has been
phosphorylated by EC 220.127.116.11.
- Enzyme II, on the other hand, is specific for a particular substrate,
although in some cases alternative substrates can be transported with
- The reaction involves a successive transfer of the phosphate group to
several amino acids within the enzyme before the final transfer to
- Formerly EC 18.104.22.168.
|PRIAM enzyme-specific profiles||22.214.171.124|
|KEGG Ligand Database for Enzyme Nomenclature||126.96.36.199|
|IUBMB Enzyme Nomenclature||188.8.131.52|
|MEDLINE||Find literature relating to 184.108.40.206|
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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.7.-.-
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