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ENZYME entry: EC 2.7.1.194
Accepted Name |
protein-N(pi)-phosphohistidine--L-ascorbate phosphotransferase.
|
Alternative Name(s) |
L-ascorbate PTS permease. |
Reaction catalysed |
L-ascorbate(out) + N(pros)-phospho-L-histidyl-[protein] <=> L-ascorbate 6-phosphate(in) + L-histidyl-[protein] |
Comment(s) |
- This enzyme is a component (known as enzyme II) of a
phosphoenolpyruvate (PEP)-dependent, sugar transporting
phosphotransferase system (PTS).
- The system, which is found only in prokaryotes, simultaneously
transports its substrate from the periplasm or extracellular space
into the cytoplasm and phosphorylates it.
- The phosphate donor, which is shared among the different systems,
is a phospho-carrier protein of low molecular mass that has been
phosphorylated by EC 2.7.3.9.
- Enzyme II, on the other hand, is specific for a particular substrate,
although in some cases alternative substrates can be transported with
lower efficiency.
- The reaction involves a successive transfer of the phosphate group to
several amino acids within the enzyme before the final transfer to
the substrate.
- Formerly EC 2.7.1.69.
|
Cross-references |
BRENDA | 2.7.1.194 |
EC2PDB | 2.7.1.194 |
ExplorEnz | 2.7.1.194 |
PRIAM enzyme-specific profiles | 2.7.1.194 |
KEGG Ligand Database for Enzyme Nomenclature | 2.7.1.194 |
IUBMB Enzyme Nomenclature | 2.7.1.194 |
IntEnz | 2.7.1.194 |
MEDLINE | Find literature relating to 2.7.1.194 |
MetaCyc | 2.7.1.194 |
Rhea expert-curated reactions | 2.7.1.194 |
UniProtKB/Swiss-Prot |
P69823, ULAB_ECO57; | Q8FAJ1, ULAB_ECOL6; | P69822, ULAB_ECOLI; |
Q9EXD8, ULAB_MYCPN; | Q57GJ8, ULAB_SALCH; | Q5PJ47, ULAB_SALPA; |
Q8Z171, ULAB_SALTI; | Q8ZK89, ULAB_SALTY; | Q31TC5, ULAB_SHIBS; |
Q328K3, ULAB_SHIDS; | Q83P29, ULAB_SHIFL; | Q3YUF4, ULAB_SHISS; |
|
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ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 2.7.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.7.-.-
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