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ENZYME

ENZYME entry: EC 2.7.1.211

Accepted Name
protein-N(pi)-phosphohistidine--sucrose phosphotransferase
Alternative Name(s)
sucrose PTS permease
Reaction catalysed
N(pros)-phospho-L-histidyl-[protein](out) + sucrose <=> L-histidyl-[protein] + sucrose 6(G)-phosphate(in)
Comment(s)
  • This enzyme is a component (known as enzyme II) of a phosphoenolpyruvate (PEP)-dependent, sugar transporting phosphotransferase system (PTS).
  • The system, which is found only in prokaryotes, simultaneously transports its substrate from the periplasm or extracellular space into the cytoplasm and phosphorylates it.
  • The phosphate donor, which is shared among the different systems, is a phospho-carrier protein of low molecular mass that has been phosphorylated by EC 2.7.3.9.
  • Enzyme II, on the other hand, is specific for a particular substrate, although in some cases alternative substrates can be transported with lower efficiency.
  • The reaction involves a successive transfer of the phosphate group to several amino acids within the enzyme before the final transfer to the substrate.
Cross-references
BRENDA2.7.1.211
EC2PDB2.7.1.211
ExplorEnz2.7.1.211
PRIAM enzyme-specific profiles2.7.1.211
KEGG Ligand Database for Enzyme Nomenclature2.7.1.211
IUBMB Enzyme Nomenclature2.7.1.211
IntEnz2.7.1.211
MEDLINEFind literature relating to 2.7.1.211
MetaCyc2.7.1.211
Rhea expert-curated reactions2.7.1.211

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.7.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.7.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-