A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.
ENZYME entry: EC 2.7.1.26
| Accepted Name |
|---|
| Riboflavin kinase.
|
| Alternative Name(s) |
|---|
| Flavokinase. |
| RFK. |
| Reaction catalysed |
|---|
| ATP + riboflavin <=> ADP + FMN |
| Cofactor(s) |
|---|
| Mg(2+) or Zn(2+) or Mn(2+).
|
| Comment(s) |
|---|
- The cofactors FMN and FAD participate in numerous processes in all
organisms, including mitochondrial electron transport,
photosynthesis, fatty-acid oxidation, and metabolism of vitamin B(6),
vitamin B12 and folates.
- While monofunctional riboflavin kinase is found in eukaryotes, some
bacteria have a bifunctional enzyme that exhibits both this activity
and that of EC 2.7.7.2.
- In Bacillus subtilis, ATP can be replaced by other phosphate donors
but with decreasing enzyme activity in the order ATP > dATP > CTP >
UTP.
|
| Cross-references |
|---|
| BRENDA | 2.7.1.26 |
| EC2PDB | 2.7.1.26 |
| ExplorEnz | 2.7.1.26 |
| PRIAM enzyme-specific profiles | 2.7.1.26 |
| KEGG Ligand Database for Enzyme Nomenclature | 2.7.1.26 |
| IUBMB Enzyme Nomenclature | 2.7.1.26 |
| IntEnz | 2.7.1.26 |
| MEDLINE | Find literature relating to 2.7.1.26 |
| MetaCyc | 2.7.1.26 |
| UniProtKB/Swiss-Prot |
| Q84MD8, FHYRK_ARATH; | Q7NBZ0, MNMA_MYCGA; | P54575, RIBC_BACSU; |
| P57250, RIBF_BUCAI; | Q8K9Z1, RIBF_BUCAP; | Q59263, RIBF_CORAM; |
| P0AG42, RIBF_ECO57; | P0AG41, RIBF_ECOL6; | P0AG40, RIBF_ECOLI; |
| A4IT50, RIBF_GEOTN; | P44957, RIBF_HAEIN; | P47391, RIBF_MYCGE; |
| P75587, RIBF_MYCPN; | P22990, RIBF_PSEFL; | O84990, RIBF_RHOOP; |
| P0AG43, RIBF_SHIFL; | P73651, RIBF_SYNY3; | P94465, RIBR_BACSU; |
| Q75DY2, RIFK_ASHGO; | A1C603, RIFK_ASPCL; | Q4WHD2, RIFK_ASPFU; |
| A2QFH1, RIFK_ASPNC; | Q2UMM4, RIFK_ASPOR; | Q0CHR1, RIFK_ASPTN; |
| Q6FM49, RIFK_CANGA; | P0C5D9, RIFK_CHAGB; | O76206, RIFK_DROME; |
| Q5AW61, RIFK_EMENI; | Q969G6, RIFK_HUMAN; | Q6CT57, RIFK_KLULA; |
| A5E1A0, RIFK_LODEL; | A4QQ05, RIFK_MAGO7; | Q8CFV9, RIFK_MOUSE; |
| A1DG00, RIFK_NEOFI; | Q6M923, RIFK_NEUCR; | A5DAH9, RIFK_PICGU; |
| A3M0C9, RIFK_PICST; | O74866, RIFK_SCHPO; | Q6CG11, RIFK_YARLI; |
| Q03778, RIFK_YEAST; |
|
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