ENZYME entry: EC 2.7.11.27
Accepted Name |
[acetyl-CoA carboxylase] kinase.
|
Alternative Name(s) |
acetyl-CoA carboxylase bound kinase. |
acetyl-CoA carboxylase kinase. |
acetyl-CoA carboxylase kinase (AMP-activated). |
acetyl-CoA carboxylase kinase (cAMP-independent). |
acetyl-coenzyme A carboxylase kinase. |
acetyl coenzyme A carboxylase kinase (phosphorylating). |
AMPK. |
I-peptide kinase. |
Reaction catalysed |
ATP + L-seryl-[acetyl-CoA carboxylase] <=> ADP + H(+) + O-phospho-L-seryl-[acetyl-CoA carboxylase] |
Comment(s) |
- Phosphorylates and inactivates EC 6.4.1.2, which can be
dephosphorylated and reactivated by EC 3.1.3.17.
- More active toward the dimeric form of acetyl-CoA carboxylase than
the polymeric form.
- Phosphorylates serine residues.
- Formerly EC 2.7.1.111 and EC 2.7.1.128.
|
Cross-references |
BRENDA | 2.7.11.27 |
EC2PDB | 2.7.11.27 |
ExplorEnz | 2.7.11.27 |
PRIAM enzyme-specific profiles | 2.7.11.27 |
KEGG Ligand Database for Enzyme Nomenclature | 2.7.11.27 |
IUBMB Enzyme Nomenclature | 2.7.11.27 |
IntEnz | 2.7.11.27 |
MEDLINE | Find literature relating to 2.7.11.27 |
MetaCyc | 2.7.11.27 |
Rhea expert-curated reactions | 2.7.11.27 |
UniProtKB/Swiss-Prot |
Q13131, AAPK1_HUMAN; | Q5EG47, AAPK1_MOUSE; | Q09136, AAPK1_PIG; |
Q5RDH5, AAPK1_PONAB; | P54645, AAPK1_RAT; | P54646, AAPK2_HUMAN; |
Q8BRK8, AAPK2_MOUSE; | Q28948, AAPK2_PIG; | Q5RD00, AAPK2_PONAB; |
Q09137, AAPK2_RAT; |
|
View entry in original ENZYME format
View entry in raw text format (no links)
All
ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 2.7.11.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.7.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-