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ENZYME entry: EC 2.7.11.3

Accepted Name
Dephospho-[reductase kinase] kinase.
Alternative Name(s)
AMP-activated kinase.
AMP-activated protein kinase kinase.
Hydroxymethylglutaryl coenzyme A reductase kinase kinase.
Reductase kinase.
Reductase kinase kinase.
Reaction catalysed
ATP + dephospho-[[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase] <=> ADP + [[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase]
Comment(s)
  • Activated by AMP and is specific for its substrate.
  • Phosphorylates and activates EC 2.7.11.31 which has been inactivated by EC 3.1.3.16.
  • Formerly EC 2.7.1.110.
Cross-references
BRENDA2.7.11.3
EC2PDB2.7.11.3
ExplorEnz2.7.11.3
PRIAM enzyme-specific profiles2.7.11.3
KEGG Ligand Database for Enzyme Nomenclature2.7.11.3
IUBMB Enzyme Nomenclature2.7.11.3
IntEnz2.7.11.3
MEDLINEFind literature relating to 2.7.11.3
MetaCyc2.7.11.3
Rhea expert-curated reactions2.7.11.3

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.7.11.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.7.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-