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ENZYME entry: EC 2.7.11.4

Accepted Name
[3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)] kinase.
Alternative Name(s)
BCK.
BCKD kinase.
BCODH kinase.
branched-chain 2-oxo acid dehydrogenase kinase.
branched-chain alpha-ketoacid dehydrogenase kinase.
branched-chain keto acid dehydrogenase kinase.
branched-chain oxo acid dehydrogenase kinase (phosphorylating).
Reaction catalysed
ATP + L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] <=> ADP + H(+) + O-phospho-L-seryl-[3-methyl-2-oxobutanoate dehydrogenase]
Comment(s)
  • Has no activating compound but is specific for its substrate.
  • A mitochondrial enzyme associated with the branched-chain 2-oxoacid dehydrogenase complex.
  • Phosphorylation inactivates EC 1.2.4.4.
  • Formerly EC 2.7.1.115.
Cross-references
BRENDA2.7.11.4
EC2PDB2.7.11.4
ExplorEnz2.7.11.4
PRIAM enzyme-specific profiles2.7.11.4
KEGG Ligand Database for Enzyme Nomenclature2.7.11.4
IUBMB Enzyme Nomenclature2.7.11.4
IntEnz2.7.11.4
MEDLINEFind literature relating to 2.7.11.4
MetaCyc2.7.11.4
Rhea expert-curated reactions2.7.11.4
UniProtKB/Swiss-Prot
Q2KJG8, BCKD_BOVIN;  O14874, BCKD_HUMAN;  O55028, BCKD_MOUSE;  
Q00972, BCKD_RAT;  

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