ENZYME entry: EC 2.7.4.14
Accepted Name |
UMP/CMP kinase.
|
Alternative Name(s) |
CMP kinase. |
cytidine monophosphate kinase. |
cytidylate kinase. |
dCMP kinase. |
deoxycytidine kinase. |
deoxycytidylate kinase. |
UMP-CMP kinase. |
uridine monophosphate-cytidine monophosphate phosphotransferase. |
Reaction catalysed |
- ATP + CMP <=> ADP + CDP
- ATP + dCMP <=> ADP + dCDP
- ATP + UMP <=> ADP + UDP
|
Comment(s) |
- This eukaryotic enzyme is a bifunctional enzyme that catalyzes the
phosphorylation of both CMP and UMP with similar efficiency.
- dCMP can also act as acceptor.
- Different from the monofunctional prokaryotic enzymes EC 2.7.4.25 and
EC 2.7.4.22.
- Formerly EC 2.7.4.5.
|
Cross-references |
BRENDA | 2.7.4.14 |
EC2PDB | 2.7.4.14 |
ExplorEnz | 2.7.4.14 |
PRIAM enzyme-specific profiles | 2.7.4.14 |
KEGG Ligand Database for Enzyme Nomenclature | 2.7.4.14 |
IUBMB Enzyme Nomenclature | 2.7.4.14 |
IntEnz | 2.7.4.14 |
MEDLINE | Find literature relating to 2.7.4.14 |
MetaCyc | 2.7.4.14 |
Rhea expert-curated reactions | 2.7.4.14 |
UniProtKB/Swiss-Prot |
Q5EBM0, CMPK2_HUMAN; | Q3U5Q7, CMPK2_MOUSE; | Q8VY84, KCY1_ARATH; |
O17622, KCY1_CAEEL; | Q5VRN0, KCY1_ORYSJ; | Q6NMK6, KCY2_ARATH; |
Q20230, KCY2_CAEEL; | Q7XMI0, KCY2_ORYSJ; | O04905, KCY3_ARATH; |
Q7XI40, KCY3_ORYSJ; | Q6K7H2, KCY4_ORYSJ; | Q2KIW9, KCY_BOVIN; |
Q5ZKE7, KCY_CHICK; | Q7ZWE9, KCY_DANRE; | P20425, KCY_DICDI; |
P30085, KCY_HUMAN; | O59845, KCY_LENED; | Q9DBP5, KCY_MOUSE; |
Q29561, KCY_PIG; | O24464, KCY_PRUAR; | Q4KM73, KCY_RAT; |
O59771, KCY_SCHPO; | Q7ZX23, KCY_XENLA; | Q28H12, KCY_XENTR; |
P15700, KCY_YEAST; |
|
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ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 2.7.4.-
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