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ENZYME entry: EC 2.7.7.42

Accepted Name
[Glutamine synthetase] adenylyltransferase.
Alternative Name(s)
[Glutamate--ammonia-ligase] adenylyltransferase.
Glutamate-ammonia-ligase adenylyltransferase.
Glutamine-synthetase adenylyltransferase.
Reaction catalysed
ATP + [glutamine synthetase]-L-tyrosine <=> diphosphate + [glutamine synthetase]-O(4)-(5'-adenylyl)-L-tyrosine
Comment(s)
  • This bacterial enzyme adenylates a tyrosine residue of EC 6.3.1.2.
  • The enzyme is bifunctional, and also catalyzes a reaction that removes the adenyl group from the modified tyrosine residue (cf. EC 2.7.7.89).
  • The two activities are present on separate domains.
Cross-references
BRENDA2.7.7.42
EC2PDB2.7.7.42
ExplorEnz2.7.7.42
PRIAM enzyme-specific profiles2.7.7.42
KEGG Ligand Database for Enzyme Nomenclature2.7.7.42
IUBMB Enzyme Nomenclature2.7.7.42
IntEnz2.7.7.42
MEDLINEFind literature relating to 2.7.7.42
MetaCyc2.7.7.42
Rhea expert-curated reactions2.7.7.42
UniProtKB/Swiss-Prot
Q6FEI9, GLNE_ACIAD;  Q8UGQ4, GLNE_AGRFC;  B4RTA0, GLNE_ALTMD;  
Q5P7S1, GLNE_AROAE;  Q6G488, GLNE_BARHE;  Q6G0B0, GLNE_BARQU;  
B3DS62, GLNE_BIFLD;  Q8G654, GLNE_BIFLO;  B7GRV5, GLNE_BIFLS;  
Q7WHH4, GLNE_BORBR;  Q7W993, GLNE_BORPA;  Q7VYQ0, GLNE_BORPE;  
Q89QJ5, GLNE_BRADU;  A5EGB0, GLNE_BRASB;  A4YRN0, GLNE_BRASO;  
Q8YG35, GLNE_BRUME;  Q8G1U0, GLNE_BRUSU;  Q62HC7, GLNE_BURMA;  
Q63R39, GLNE_BURPS;  Q9A4S7, GLNE_CAUVC;  Q7NW95, GLNE_CHRVO;  
A8APT2, GLNE_CITK8;  Q6NG61, GLNE_CORDI;  Q8FNL8, GLNE_COREF;  
Q79VE2, GLNE_CORGL;  Q6A9Z4, GLNE_CUTAK;  B7UIW1, GLNE_ECO27;  
B7MAC9, GLNE_ECO45;  Q8XBM3, GLNE_ECO57;  B5YR92, GLNE_ECO5E;  
B7NJR6, GLNE_ECO7I;  B7N0K2, GLNE_ECO81;  B7LZK2, GLNE_ECO8A;  
C4ZQX0, GLNE_ECOBW;  B1XG58, GLNE_ECODH;  A8A4K7, GLNE_ECOHS;  
Q8FDH4, GLNE_ECOL6;  B1IRR3, GLNE_ECOLC;  P30870, GLNE_ECOLI;  
B7ND41, GLNE_ECOLU;  B6I424, GLNE_ECOSE;  B1LF44, GLNE_ECOSM;  
B7LQD0, GLNE_ESCF3;  Q7VKZ4, GLNE_HAEDU;  P44419, GLNE_HAEIN;  
Q2SN48, GLNE_HAHCH;  Q5QY18, GLNE_IDILO;  B5XU39, GLNE_KLEP3;  
A6TE32, GLNE_KLEP7;  Q6AFH2, GLNE_LEIXX;  Q9FD13, GLNE_MANHA;  
Q65T25, GLNE_MANSM;  Q605D9, GLNE_METCA;  A0QEW1, GLNE_MYCA1;  
P69941, GLNE_MYCBO;  Q9CBT4, GLNE_MYCLE;  B2HHM1, GLNE_MYCMM;  
Q73YJ1, GLNE_MYCPA;  A0R082, GLNE_MYCS2;  P9WN26, GLNE_MYCTO;  
P9WN27, GLNE_MYCTU;  A0PNH1, GLNE_MYCUA;  Q9JX72, GLNE_NEIMA;  
Q9K1D5, GLNE_NEIMB;  Q0AGL4, GLNE_NITEC;  Q81ZZ7, GLNE_NITEU;  
Q3JES8, GLNE_NITOC;  Q5YZ84, GLNE_NOCFA;  Q9CNQ2, GLNE_PASMU;  
Q6D163, GLNE_PECAS;  Q7N0C2, GLNE_PHOLL;  Q6LUZ6, GLNE_PHOPR;  
B4EW47, GLNE_PROMH;  Q9HUF4, GLNE_PSEAE;  Q88QZ4, GLNE_PSEPK;  
Q87VD5, GLNE_PSESM;  A1SRE0, GLNE_PSYIN;  Q8XW19, GLNE_RALSO;  
Q985F6, GLNE_RHILO;  Q92R86, GLNE_RHIME;  Q2IUH4, GLNE_RHOP2;  
Q6N8H0, GLNE_RHOPA;  Q139J0, GLNE_RHOPS;  B3QBR5, GLNE_RHOPT;  
B5F697, GLNE_SALA4;  A9MPW2, GLNE_SALAR;  Q57JQ8, GLNE_SALCH;  
B5FHT6, GLNE_SALDC;  B5QZ37, GLNE_SALEP;  B5REF9, GLNE_SALG2;  
B4TI52, GLNE_SALHS;  B4T671, GLNE_SALNS;  Q5PC85, GLNE_SALPA;  
A9N5X9, GLNE_SALPB;  C0PYX4, GLNE_SALPC;  B5BG12, GLNE_SALPK;  
B4TVT5, GLNE_SALSV;  Q8Z3N1, GLNE_SALTI;  Q8ZLY6, GLNE_SALTY;  
A8GJU4, GLNE_SERP5;  A1S909, GLNE_SHEAM;  Q07Y17, GLNE_SHEFN;  
A3QAK2, GLNE_SHELP;  Q8EAY1, GLNE_SHEON;  A8G014, GLNE_SHESH;  
B1KE36, GLNE_SHEWM;  B2U1F8, GLNE_SHIB3;  Q31WY2, GLNE_SHIBS;  
Q32BR1, GLNE_SHIDS;  Q7UBI7, GLNE_SHIFL;  Q3YXI9, GLNE_SHISS;  
Q81ZW1, GLNE_STRAW;  Q8CK02, GLNE_STRCO;  B4SHL3, GLNE_STRM5;  
B2FKU9, GLNE_STRMK;  B8GL43, GLNE_THISH;  Q9KPD4, GLNE_VIBCH;  
Q87SK0, GLNE_VIBPA;  Q8DEH6, GLNE_VIBVU;  Q7MNY4, GLNE_VIBVY;  
Q8PPY3, GLNE_XANAC;  Q4UZ80, GLNE_XANC8;  B0RN79, GLNE_XANCB;  
Q8P4V7, GLNE_XANCP;  Q2NY41, GLNE_XANOM;  A7IL55, GLNE_XANP2;  
A1JQV7, GLNE_YERE8;  A7FE78, GLNE_YERP3;  Q1C373, GLNE_YERPA;  
B2K2H5, GLNE_YERPB;  Q8ZI61, GLNE_YERPE;  A9R7D6, GLNE_YERPG;  
Q1CMD5, GLNE_YERPN;  A4THT8, GLNE_YERPP;  Q665V2, GLNE_YERPS;  
B1JM25, GLNE_YERPY;  

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