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ENZYME

ENZYME entry: EC 6.3.1.2

Accepted Name
glutamine synthetase
Alternative Name(s)
glutamate--ammonia ligase
L-glutamine synthetase
Reaction catalysed
ATP + L-glutamate + NH4(+) <=> ADP + H(+) + L-glutamine + phosphate
Comment(s)
  • Glutamine synthetase, which catalyzes the incorporation of ammonium into glutamate, is a key enzyme of nitrogen metabolism found in all domains of life.
  • Several types have been described, differing in their oligomeric structures and cofactor requirements.
Cross-references
BRENDA6.3.1.2
EC2PDB6.3.1.2
ExplorEnz6.3.1.2
PRIAM enzyme-specific profiles6.3.1.2
KEGG Ligand Database for Enzyme Nomenclature6.3.1.2
IUBMB Enzyme Nomenclature6.3.1.2
IntEnz6.3.1.2
MEDLINEFind literature relating to 6.3.1.2
MetaCyc6.3.1.2
Rhea expert-curated reactions6.3.1.2
UniProtKB/Swiss-Prot
Q56WN1, GLN11_ARATHP14656, GLN11_ORYSJQ8LCE1, GLN12_ARATH
P14654, GLN12_ORYSJQ9LVI8, GLN13_ARATHQ4W8D0, GLN13_ORYSJ
Q9FMD9, GLN14_ARATHQ8GXW5, GLN15_ARATHP19064, GLN1A_BACCE
P12425, GLN1A_BACSUP10656, GLN1A_CLOSAP45627, GLN1A_LACDE
Q9CDL9, GLN1A_LACLAP64246, GLN1A_MYCBOA0R083, GLN1A_MYCS2
P9WN36, GLN1A_MYCTOP9WN37, GLN1A_MYCTUQ5HGC3, GLN1A_STAAC
P60890, GLN1A_STAAMP99095, GLN1A_STAANQ6GHC6, GLN1A_STAAR
Q6G9Q4, GLN1A_STAASP0A040, GLN1A_STAAUP0A039, GLN1A_STAAW
Q5HPN2, GLN1A_STAEQQ8CSR8, GLN1A_STAESP36205, GLN1A_THEMA
P07804, GLN1B_ACIFRO66514, GLN1B_AQUAEP10583, GLN1B_AZOBR
P94126, GLN1B_AZOC5P22248, GLN1B_AZOVIP05457, GLN1B_BRADU
P43518, GLN1B_CERSPP0A9C7, GLN1B_ECO57P0A9C6, GLN1B_ECOL6
P0A9C5, GLN1B_ECOLIP46033, GLN1B_FRAALP43794, GLN1B_HAEIN
Q9ZLW5, GLN1B_HELPJP94845, GLN1B_HELPYP15124, GLN1B_METCA
P33035, GLN1B_MICDPP0A591, GLN1B_MYCBOA0R079, GLN1B_MYCS2
P9WN38, GLN1B_MYCTOP9WN39, GLN1B_MYCTUP25821, GLN1B_NEIGO
P00964, GLN1B_NOSS1Q9CLP2, GLN1B_PASMUP20479, GLN1B_PHOLP
P28786, GLN1B_PROHUQ9HU65, GLN1B_PSEAEQ3V5W6, GLN1B_PSETA
P09826, GLN1B_RHILVQ59747, GLN1B_RHIMEP13499, GLN1B_RHOCA
P0A1P7, GLN1B_SALTIP0A1P6, GLN1B_SALTYP0A9C8, GLN1B_SHIFL
P15106, GLN1B_STRCOP77958, GLN1B_STRFLQ05542, GLN1B_STRVR
P28605, GLN1B_SYNP2P77961, GLN1B_SYNY3P51120, GLN1B_TRITH
P19904, GLN1B_VIBALQ9KNJ2, GLN1B_VIBCHO04867, GLNA1_ALNGL
Q42688, GLNA1_CHLREO22504, GLNA1_DAUCAQ86B00, GLNA1_DICDI
P20477, GLNA1_DROMEQ42899, GLNA1_LOTJAP38559, GLNA1_MAIZE
P04078, GLNA1_MEDSAQ8PY99, GLNA1_METMAP08282, GLNA1_PEA
P04770, GLNA1_PHAVUP24099, GLNA1_SOYBNP51118, GLNA1_VITVI
Q43127, GLNA2_ARATHP04772, GLNA2_BRADUQ42689, GLNA2_CHLRE
O22506, GLNA2_DAUCAP0C7B6, GLNA2_DICDIP20478, GLNA2_DROME
P81643, GLNA2_EMIHUP20805, GLNA2_FRAALP13564, GLNA2_HORVU
P38560, GLNA2_MAIZEQ9XQ94, GLNA2_MEDSAP14655, GLNA2_ORYSJ
P08281, GLNA2_PEAP04771, GLNA2_PHAVUP81107, GLNA2_PINPS
Q02154, GLNA2_RHILPP45626, GLNA2_RHIMLO82560, GLNA2_SOYBN
P22878, GLNA2_STRHYP19432, GLNA2_STRVRP51119, GLNA2_VITVI
P15623, GLNA3_BACFRQ05650, GLNA3_BUTFIQ54WR9, GLNA3_DICDI
I3R176, GLNA3_HALMTQ06378, GLNA3_HORVUP14636, GLNA3_LUPAN
P38561, GLNA3_MAIZEQ43785, GLNA3_MEDSAP07694, GLNA3_PEA
P00965, GLNA3_PHAVUP31592, GLNA3_RHILPO87393, GLNA3_RHIME
P38562, GLNA4_MAIZEQ43066, GLNA4_PEAP15102, GLNA4_PHAVU
P38563, GLNA5_MAIZEQ42624, GLNAC_BRANAP25462, GLNAC_MAIZE
Q9QY94, GLNA_ACOCAO00088, GLNA_AGABIQ8X169, GLNA_AMAMU
O29313, GLNA_ARCFUQ75BT9, GLNA_ASHGOP15103, GLNA_BOVIN
P34497, GLNA_CAEELQ6FMT6, GLNA_CANGBQ8HZM5, GLNA_CANLF
P16580, GLNA_CHICKQ12613, GLNA_COLGLP04773, GLNA_CRIGR
P0CN85, GLNA_CRYNBP0CN84, GLNA_CRYNJQ6B4U7, GLNA_DEBHA
P11600, GLNA_DUNSAQ96V52, GLNA_EMENIQ9UUN6, GLNA_FUSSH
Q9C2U9, GLNA_GIBFUQ9HNI2, GLNA_HALSAP43386, GLNA_HALVD
Q96UV5, GLNA_HEBCYP15104, GLNA_HUMANQ874T6, GLNA_KLULC
P23712, GLNA_LACSAP52782, GLNA_LUPLUQ4R7U3, GLNA_MACFA
Q60182, GLNA_METJAO59648, GLNA_METMPO27612, GLNA_METTH
P21154, GLNA_METVOQ5UR44, GLNA_MIMIVP15105, GLNA_MOUSE
Q86ZF9, GLNA_NEUCRP12424, GLNA_NICPLQ04831, GLNA_PANAR
P46410, GLNA_PIGP52783, GLNA_PINSYQ9UY99, GLNA_PYRAB
Q05907, GLNA_PYRFUO58097, GLNA_PYRHOP36687, GLNA_PYRWO
P09606, GLNA_RATP23794, GLNA_SACS2Q09179, GLNA_SCHPO
P41320, GLNA_SQUACQ8J1R3, GLNA_SUIBOQ9HH09, GLNA_SULAC
O08467, GLNA_THEKOQ5SIP0, GLNA_THET8Q86ZU6, GLNA_TUBBO
P32289, GLNA_VIGACP85087, GLNA_VITSXP51121, GLNA_XENLA
Q6C3E0, GLNA_YARLIP32288, GLNA_YEAST

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All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 6.3.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 6.3.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 6.-.-.-