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ENZYME

ENZYME entry: EC 2.7.7.50

Accepted Name
mRNA guanylyltransferase
Alternative Name(s)
GTP--RNA guanylyltransferase
mRNA capping enzyme
Reaction catalysed
a 5'-end diphospho-ribonucleoside in mRNA + GTP + H(+) = a 5'-end (5'-triphosphoguanosine)-ribonucleoside in mRNA + diphosphate
Comment(s)
The human enzyme is a multi domain protein that also has the activity of EC 3.6.1.74.
Cross-references
BRENDA2.7.7.50
EC2PDB2.7.7.50
ExplorEnz2.7.7.50
PRIAM enzyme-specific profiles2.7.7.50
KEGG Ligand Database for Enzyme Nomenclature2.7.7.50
IUBMB Enzyme Nomenclature2.7.7.50
IntEnz2.7.7.50
MEDLINEFind literature relating to 2.7.7.50
MetaCyc2.7.7.50
Rhea expert-curated reactions2.7.7.50
UniProtKB/Swiss-Prot
P41477, LEF4_NPVACP11079, LMBD2_REOVDQ91RA4, LMBD2_REOVJ
Q91RA6, LMBD2_REOVLQ17607, MCE1_CAEELP78587, MCE1_CANAX
Q6FQ31, MCE1_CANGAQ6NY98, MCE1_DANREQ6BT58, MCE1_DEBHA
Q755D0, MCE1_EREGSO60942, MCE1_HUMANQ6CWR0, MCE1_KLULA
O55236, MCE1_MOUSEQ7SB53, MCE1_NEUCRP40997, MCE1_SCHPO
Q6C783, MCE1_YARLIQ01159, MCE1_YEASTQ8V2R8, MCEL_CAMPM
Q775U0, MCEL_CAMPSQ8QMV9, MCEL_CWPXBQ80DX6, MCEL_CWPXG
Q9J584, MCEL_FOWPNA0A7H0DN85, MCEL_MONPVP25950, MCEL_RFVKA
O57209, MCEL_VACCAP20979, MCEL_VACCCQ9JFA8, MCEL_VACCT
P04298, MCEL_VACCWP0DSX5, MCEL_VAR67P0DSX6, MCEL_VARV
P32094, MCE_ASFB7P0C995, MCE_ASFK5Q65216, MCE_ASFM2
P0C993, MCE_ASFP4P0C994, MCE_ASFWAQ5UQX1, MCE_MIMIV
Q84424, MCE_PBCV1P14583, MCE_RDVAQ85437, MCE_RDVF
Q1WNZ7, MCE_RGDVP12366, MCE_WTVP0C6W1, R1AB_BC133
P0C6V9, R1AB_BC279P0C6W0, R1AB_BC512P0C6W2, R1AB_BCHK3
P0C6W3, R1AB_BCHK4P0C6W4, R1AB_BCHK5P0C6W5, R1AB_BCHK9
P0C6W6, R1AB_BCRP3P0C6W7, R1AB_CVBENP0C6W8, R1AB_CVBLU
P0C6W9, R1AB_CVBMP0C6X0, R1AB_CVBQP0C6X1, R1AB_CVH22
P0C6X2, R1AB_CVHN1P0C6X3, R1AB_CVHN2P0C6X4, R1AB_CVHN5
P0C6X5, R1AB_CVHNLP0C6X6, R1AB_CVHOCP0C6X8, R1AB_CVM2
P0C6X9, R1AB_CVMA5P0C6Y0, R1AB_CVMJHP0C6Y5, R1AB_CVPPU
Q98VG9, R1AB_FIPVP0C6Y1, R1AB_IBVBP0C6Y2, R1AB_IBVBC
P0C6Y3, R1AB_IBVMK9N7C7, R1AB_MERS1P0C6Y4, R1AB_PEDV7
P0C6X7, R1AB_SARSP0DTD1, R1AB_SARS2P0C6F7, R1A_BC133
P0C6F5, R1A_BC279P0C6F8, R1A_BCHK3P0C6T4, R1A_BCHK4
P0C6T5, R1A_BCHK5P0C6T6, R1A_BCHK9P0C6T7, R1A_BCRP3
P0C6T8, R1A_CVBENP0C6T9, R1A_CVBLUP0C6U0, R1A_CVBM
P0C6U1, R1A_CVBQP0C6U3, R1A_CVHN1P0C6U4, R1A_CVHN2
P0C6U5, R1A_CVHN5P0C6U7, R1A_CVHOCP0C6U9, R1A_CVM2
P0C6V0, R1A_CVMA5P0C6V1, R1A_CVMJHK9N638, R1A_MERS1
P0C6V6, R1A_PEDV7P0C6U8, R1A_SARSP0DTC1, R1A_SARS2
Q8VA43, VP1_AQRVAQ8JU62, VP1_AQRVCB2BND9, VP1_AQRVG
O56043, VP2_RRSVTQ9INI4, VP3_BAVJKQ7TDB4, VP3_MYRV9
Q3ZK57, VP3_ROT41B1NKR5, VP3_ROTADA9Q1K9, VP3_ROTB2
A7J3A0, VP3_ROTBNQ65526, VP3_ROTBSQ6WAT6, VP3_ROTBU
Q6WNV6, VP3_ROTCCQ6WNV7, VP3_ROTELA4ZCW6, VP3_ROTH3
Q6WNW3, VP3_ROTH6B1NKR1, VP3_ROTH7Q82041, VP3_ROTHC
Q6WNW5, VP3_ROTHDQ9QNB1, VP3_ROTHKB1NKS7, VP3_ROTHL
B1NKT1, VP3_ROTHPA7J392, VP3_ROTHSB1NKT9, VP3_ROTHT
Q91HJ9, VP3_ROTHUQ6WVH5, VP3_ROTHWQ45UF7, VP3_ROTJ1
Q6WNV8, VP3_ROTP5P26192, VP3_ROTPCQ8BB04, VP3_ROTRF
P15736, VP3_ROTS1A2T3S5, VP3_ROTSHB3F2X7, VP3_ROTTU
B2BMF9, VP3_ROTW3B1NKU3, VP3_ROTWIA7J3A4, VP3_ROTYO
Q91ID8, VP4_LDCPRQ2Y0E6, VP5_APRVF

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.7.7.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.7.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-