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ENZYME

ENZYME entry: EC 2.7.7.74

PURL: https://purl.expasy.org/enzyme/EC/2.7.7.74
Accepted Name
1L-myo-inositol 1-phosphate cytidylyltransferase
Alternative Name(s)
IPCT
L-myo-inositol-1-phosphate cytidylyltransferase
Reaction catalysed
1D-myo-inositol 3-phosphate + CTP + H(+) = CDP-1L-myo-inositol + diphosphate
Comment(s)
  • In many organisms this activity is catalyzed by a bifunctional enzyme.
  • The cytidylyltransferase domain of the bifunctional EC 2.7.7.74/EC 2.7.8.34 is absolutely specific for CTP and 1L-myo- inositol 1-phosphate.
  • The enzyme is involved in biosynthesis of bis(1L-myo-inositol) 1,3'-phosphate, a widespread organic solute in microorganisms adapted to hot environments.
Cross-references
BRENDA2.7.7.74
EC2PDB2.7.7.74
ExplorEnz2.7.7.74
KEGG Ligand Database for Enzyme Nomenclature2.7.7.74
IUBMB Enzyme Nomenclature2.7.7.74
MEDLINEFind literature relating to 2.7.7.74
MetaCyc2.7.7.74
Rhea expert-curated reactions2.7.7.74
UniProtKB/Swiss-Prot
O67379, DIPPS_AQUAEO29976, DIPPS_ARCFUQ8U1Z6, DIPPS_PYRFU
Q1AWQ0, DIPPS_RUBXDQ5JDA9, DIPPS_THEKO

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