A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.
ENZYME entry: EC 2.7.7.74
| Accepted Name |
|---|
| 1L-myo-inositol 1-phosphate cytidylyltransferase.
|
| Alternative Name(s) |
|---|
| IPCT. |
| L-myo-inositol-1-phosphate cytidylyltransferase. |
| Reaction catalysed |
|---|
| CTP + 1L-myo-inositol 1-phosphate <=> diphosphate + CDP-1L-myo-inositol |
| Comment(s) |
|---|
- In many organisms this activity is catalyzed by a bifunctional
enzyme.
- The cytidylyltransferase domain of the bifunctional
EC 2.7.7.74/EC 2.7.8.34 (CTP:inositol-1-phosphate
cytidylyltransferase/CDP-inositol:inositol-1-phosphate transferase)
is absolutely specific for CTP and 1L-myo-inositol 1-phosphate.
- The enzyme is involved in biosynthesis of bis(1L-myo-inositol)
1,3'-phosphate, a widespread organic solute in microorganisms adapted
to hot environments.
- In many organisms this activity is catalyzed by a bifunctional
enzyme.
- The cytidylyltransferase domain of the bifunctional
EC 2.7.7.74/EC 2.7.8.34 is absolutely specific for CTP and 1L-myo-
inositol 1-phosphate.
- The enzyme is involved in biosynthesis of bis(1L-myo-inositol)
1,3'-phosphate, a widespread organic solute in microorganisms adapted
to hot environments.
|
| Cross-references |
|---|
| BRENDA | 2.7.7.74 |
| EC2PDB | 2.7.7.74 |
| ExplorEnz | 2.7.7.74 |
| PRIAM enzyme-specific profiles | 2.7.7.74 |
| KEGG Ligand Database for Enzyme Nomenclature | 2.7.7.74 |
| IUBMB Enzyme Nomenclature | 2.7.7.74 |
| IntEnz | 2.7.7.74 |
| MEDLINE | Find literature relating to 2.7.7.74 |
| MetaCyc | 2.7.7.74 |
| UniProtKB/Swiss-Prot |
|
View entry in original ENZYME format
View entry in raw text format (no links)
All
ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 2.7.7.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.7.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-