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A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.

ENZYME entry: EC 2.7.7.93

Accepted Name
Phosphonoformate cytidylyltransferase.
Reaction catalysed
CTP + phosphonoformate <=> CMP-5'-phosphonoformate + diphosphate
Comment(s)
  • The enzyme, characterized from the bacterium Streptomyces viridochromogenes, participates in the biosynthesis of the herbicide antibiotic bialaphos.
  • The enzyme from the bacterium Kitasatospora phosalacinea participates in the biosynthesis of the related compound phosalacine.
  • Both compounds contain the nonproteinogenic amino acid L-phosphinothricin that acts as a potent inhibitor of EC 6.3.1.2.
Cross-references
BRENDA2.7.7.93
EC2PDB2.7.7.93
ExplorEnz2.7.7.93
PRIAM enzyme-specific profiles2.7.7.93
KEGG Ligand Database for Enzyme Nomenclature2.7.7.93
IUBMB Enzyme Nomenclature2.7.7.93
IntEnz2.7.7.93
MEDLINEFind literature relating to 2.7.7.93
MetaCyc2.7.7.93

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.7.7.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.7.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-