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A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.

ENZYME entry: EC

Accepted Name
3-hydroxy-4-methylanthranilate adenylyltransferase.
Alternative Name(s)
4-MHA-activating enzyme.
Actinomycin synthase I.
Reaction catalysed
ATP + 3-hydroxy-4-methylanthranilate <=> diphosphate + 3-hydroxy-4-methylanthranilyl-adenylate
The enzyme, characterized from the bacteria Streptomyces anulatus and Streptosporangium sibiricum, activates 3-hydroxy-4- methylanthranilate, a precursor of actinomycin antibiotics and the antitumor antibiotic sibiromycin, to an adenylate form, so it can be loaded onto a dedicated aryl-carrier protein.
PRIAM enzyme-specific profiles2.7.7.97
KEGG Ligand Database for Enzyme Nomenclature2.7.7.97
IUBMB Enzyme Nomenclature2.7.7.97
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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.7.7.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.7.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-