A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.
ENZYME entry: EC 2.7.8.12
| Accepted Name |
|---|
| Teichoic acid poly(glycerol phosphate) polymerase.
|
| Alternative Name(s) |
|---|
| Poly(glycerol phosphate) polymerase. |
| Tag polymerase. |
| Teichoic acid glycerol transferase. |
| Teichoic-acid synthase. |
| Reaction catalysed |
|---|
| n CDP-glycerol + 4-O-((2R)-glycerophospho)-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol <=> n CMP + 4-O-(((2R)-glycerophospho)n-(2R)-glycerophospho)-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol |
| Comment(s) |
|---|
- Involved in the biosynthesis of poly glycerol phosphate teichoic
acids in bacterial cell walls.
- This enzyme adds 30-50 glycerol units to the linker molecule,
but only after it has been primed with the first glycerol unit by
EC 2.7.8.44.
- Cf. EC 2.7.8.45.
|
| Cross-references |
|---|
| BRENDA | 2.7.8.12 |
| EC2PDB | 2.7.8.12 |
| ExplorEnz | 2.7.8.12 |
| PRIAM enzyme-specific profiles | 2.7.8.12 |
| KEGG Ligand Database for Enzyme Nomenclature | 2.7.8.12 |
| IUBMB Enzyme Nomenclature | 2.7.8.12 |
| IntEnz | 2.7.8.12 |
| MEDLINE | Find literature relating to 2.7.8.12 |
| MetaCyc | 2.7.8.12 |
| UniProtKB/Swiss-Prot |
|
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ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 2.7.8.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.7.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-