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ENZYME entry: EC 2.7.8.45

Accepted Name
teichoic acid glycerol-phosphate transferase.
Alternative Name(s)
teichoic acid glycerol-phosphate primase.
Reaction catalysed
4-O-[(2R)-glycerylphospho]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl di-trans,octa-cis-undecaprenyl diphosphate + CDP-glycerol <=> 4-O-[di(2R)-glycerylphospho]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl di-trans,octa-cis-undecaprenyl diphosphate + CMP + H(+)
Comment(s)
  • Involved in the biosynthesis of teichoic acid linkage units in the cell walls of some bacteria such as Staphylococcus aureus.
  • This enzyme adds a second glycerol unit to the disaccharide linker of the teichoic acid.
  • Cf. EC 2.7.8.12.
Cross-references
BRENDA2.7.8.45
EC2PDB2.7.8.45
ExplorEnz2.7.8.45
PRIAM enzyme-specific profiles2.7.8.45
KEGG Ligand Database for Enzyme Nomenclature2.7.8.45
IUBMB Enzyme Nomenclature2.7.8.45
IntEnz2.7.8.45
MEDLINEFind literature relating to 2.7.8.45
MetaCyc2.7.8.45
Rhea expert-curated reactions2.7.8.45
UniProtKB/Swiss-Prot
Q2G1C1, TARF_STAA8

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