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ENZYME entry: EC 2.7.8.43

Accepted Name
Lipid A phosphoethanolamine transferase.
Alternative Name(s)
Lipid A PEA transferase.
Reaction catalysed
  • Diacylphosphatidylethanolamine + lipid A <=> diacylglycerol + lipid A 1-(2-aminoethyl diphosphate)
  • Diacylphosphatidylethanolamine + lipid A <=> diacylglycerol + lipid A 4'-(2-aminoethyl diphosphate)
  • Diacylphosphatidylethanolamine + lipid A 1-(2-aminoethyl diphosphate) <=> diacylglycerol + lipid A 1,4'-bis(2-aminoethyl diphosphate)
Comment(s)
  • The enzyme adds one or two ethanolamine phosphate groups to lipid A giving a diphosphate, sometimes in combination with EC 2.4.2.43 giving products with 4-amino-4-deoxy-beta-L-arabinose groups at the phosphates of lipid A instead of diphosphoethanolamine groups.
  • It will also act on lipid IV(A) and Kdo(2)-lipid A.
  • Formerly EC 2.7.4.30.
Cross-references
BRENDA2.7.8.43
EC2PDB2.7.8.43
ExplorEnz2.7.8.43
PRIAM enzyme-specific profiles2.7.8.43
KEGG Ligand Database for Enzyme Nomenclature2.7.8.43
IUBMB Enzyme Nomenclature2.7.8.43
IntEnz2.7.8.43
MEDLINEFind literature relating to 2.7.8.43
MetaCyc2.7.8.43
Rhea expert-curated reactions2.7.8.43

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.7.8.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.7.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-