Expasy logo

ENZYME

ENZYME entry: EC 2.7.8.43

Accepted Name
lipid A phosphoethanolamine transferase
Alternative Name(s)
lipid A PEA transferase
Reaction catalysed
  • a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + H(+) + lipid A (E. coli) <=> a 1,2-diacyl-sn-glycerol + lipid A hexaacyl 1-(2-aminoethyl diphosphate)
  • a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + H(+) + lipid A (E. coli) <=> a 1,2-diacyl-sn-glycerol + lipid A 4'-(2-aminoethyl diphosphate) (E. coli)
  • a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + H(+) + lipid A hexaacyl 1-(2-aminoethyl diphosphate) <=> a 1,2-diacyl-sn-glycerol + lipid A 1,4'-bis(2-aminoethyl diphosphate)
Comment(s)
  • The enzyme adds one or two ethanolamine phosphate groups to lipid A giving a diphosphate, sometimes in combination with EC 2.4.2.43 giving products with 4-amino-4-deoxy-beta-L-arabinose groups at the phosphates of lipid A instead of diphosphoethanolamine groups.
  • It will also act on lipid IVA and Kdo2-lipid A.
  • Formerly EC 2.7.4.30.
Cross-references
BRENDA2.7.8.43
EC2PDB2.7.8.43
ExplorEnz2.7.8.43
PRIAM enzyme-specific profiles2.7.8.43
KEGG Ligand Database for Enzyme Nomenclature2.7.8.43
IUBMB Enzyme Nomenclature2.7.8.43
IntEnz2.7.8.43
MEDLINEFind literature relating to 2.7.8.43
MetaCyc2.7.8.43
Rhea expert-curated reactions2.7.8.43

View entry in original ENZYME format
View entry in raw text format (no links)
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.7.8.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.7.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-