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ENZYME entry: EC 3.1.1.101

Accepted Name
poly(ethylene terephthalate) hydrolase.
Alternative Name(s)
PETase.
PET hydrolase.
Reaction catalysed
(ethylene terephthalate)(n) + H2O <=> (ethylene terephthalate)(n-1) + 4-[(2-hydroxyethoxy)carbonyl]benzoate + H(+)
Comment(s)
  • The enzyme, isolated from the bacterium Ideonella sakaiensis, also produces small amounts of terephthalate (cf. EC 3.1.1.102).
  • The reaction takes place on PET-film placed in solution.
Cross-references
BRENDA3.1.1.101
EC2PDB3.1.1.101
ExplorEnz3.1.1.101
PRIAM enzyme-specific profiles3.1.1.101
KEGG Ligand Database for Enzyme Nomenclature3.1.1.101
IUBMB Enzyme Nomenclature3.1.1.101
IntEnz3.1.1.101
MEDLINEFind literature relating to 3.1.1.101
MetaCyc3.1.1.101
Rhea expert-curated reactions3.1.1.101
UniProtKB/Swiss-Prot
D4Q9N1, PETH1_THEAE;  E9LVH8, PETH1_THECS;  G8GER6, PETH1_THEFU;  
Q47RJ7, PETH1_THEFY;  F7IX06, PETH2_THEAE;  E9LVH9, PETH2_THECS;  
Q6A0I4, PETH2_THEFU;  Q47RJ6, PETH2_THEFY;  A0A0K8P6T7, PETH_IDESA;  
G9BY57, PETH_UNKP;  

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