Home  |  Contact

ENZYME entry: EC 3.1.1.106

Accepted Name
O-acetyl-ADP-ribose deacetylase.
Reaction catalysed
  • 3''-O-acetyl-ADP-D-ribose + H(2)O <=> ADP-D-ribose + acetate
  • 2''-O-acetyl-ADP-D-ribose + H(2)O <=> ADP-D-ribose + acetate
Comment(s)
  • The enzyme, characterized from the bacterium Escherichia coli and from human cells, removes the acetyl group from either the 2'' or 3'' position of O-acetyl-ADP-ribose, which are formed by the action of EC 2.3.1.286.
  • The human enzyme can also remove ADP-D-ribose from phosphorylated double stranded DNA adducts.
Cross-references
BRENDA3.1.1.106
EC2PDB3.1.1.106
ExplorEnz3.1.1.106
PRIAM enzyme-specific profiles3.1.1.106
KEGG Ligand Database for Enzyme Nomenclature3.1.1.106
IUBMB Enzyme Nomenclature3.1.1.106
IntEnz3.1.1.106
MEDLINEFind literature relating to 3.1.1.106
MetaCyc3.1.1.106
UniProtKB/Swiss-Prot
Q2KHU5, MACD1_BOVIN;  Q9BQ69, MACD1_HUMAN;  Q922B1, MACD1_MOUSE;  
Q8K4G6, MACD1_RAT;  E1SDF1, YMDB1_PANVC;  E1PL40, YMDB2_PANVC;  
A8AI35, YMDB_CITK8;  D2TT52, YMDB_CITRI;  A7MG20, YMDB_CROS8;  
C9Y0V8, YMDB_CROTZ;  P0A8D8, YMDB_ECO57;  P0A8D7, YMDB_ECOL6;  
P0A8D6, YMDB_ECOLI;  A4W960, YMDB_ENT38;  D5CE05, YMDB_ENTCC;  
B7LT90, YMDB_ESCF3;  B5XXK9, YMDB_KLEP3;  D3RKJ0, YMDB_KLEVT;  
B5F961, YMDB_SALA4;  B5RBF3, YMDB_SALG2;  B4T2X8, YMDB_SALNS;  
P67342, YMDB_SALTI;  P67341, YMDB_SALTY;  Q32E73, YMDB_SHIDS;  
Q0T5Z6, YMDB_SHIF8;  

View entry in original ENZYME format
View entry in raw text format (no links)
All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.1.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.1.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.-.-.-