Home  |  Contact

ENZYME entry: EC 3.1.1.107

Accepted Name
apo-salmochelin esterase.
Reaction catalysed
  • enterobactin + H2O <=> N-(2,3-dihydroxybenzoyl)-L-serine trimer
  • H2O + triglucosyl-enterobactin <=> [N-(C-5-[deoxy-beta-D-glucosyl]-2,3-dihydroxybenzoyl)-L-serine]3 + H(+)
  • diglucosyl-enterobactin + H2O <=> H(+) + N-(2,3-dihydroxybenzoyl)-L-seryl-[N-(C-5-[deoxy-beta-D-glucosyl]-2,3-dihydroxybenzoyl)-L-serine]2
  • H2O + monoglucosyl-enterobactin <=> [N-(2,3-dihydroxybenzoyl)-L-seryl]2-N-(C-5-[deoxy-beta-D-glucosyl]-2,3-dihydroxybenzoyl)-L-serine + H(+)
Comment(s)
  • This bacterial enzyme is present in pathogenic Salmonella species, uropathogenic and avian pathogenic Escherichia coli strains, and certain Klebsiella strains.
  • Unlike EC 3.1.1.108, which acts only on enterobactin, this enzyme can also act on the C-glucosylated forms known as salmochelins.
  • Unlike EC 3.1.1.109, (IroD), IroE prefers apo siderophores as substrates, and is assumed to act before the siderophores are exported out of the cell.
  • It hydrolyzes the trilactone only once, producing linearized trimers.
Cross-references
BRENDA3.1.1.107
EC2PDB3.1.1.107
ExplorEnz3.1.1.107
PRIAM enzyme-specific profiles3.1.1.107
KEGG Ligand Database for Enzyme Nomenclature3.1.1.107
IUBMB Enzyme Nomenclature3.1.1.107
IntEnz3.1.1.107
MEDLINEFind literature relating to 3.1.1.107
MetaCyc3.1.1.107
Rhea expert-curated reactions3.1.1.107
UniProtKB/Swiss-Prot
A0A0H2V871, IROE_ECOL6

View entry in original ENZYME format
View entry in raw text format (no links)
All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.1.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.1.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.-.-.-