ENZYME entry: EC 3.1.1.109
Accepted Name |
Iron(III) salmochelin esterase.
|
Reaction catalysed |
- Iron(III)-[diglucosyl-enterobactin] complex + H(2)O <=> iron(III)-[salmochelin S2] complex
- Iron(III)-[monoglucosyl-enterobactin] complex + H(2)O <=> iron(III)-[monoglucosyl-(2,3-dihydroxybenzoylserine)(3)] complex
- Iron(III)-[salmochelin S2] complex + H(2)O <=> iron(III)-[diglucosyl-(2,3-dihydroxybenzoylserine)(2)] complex + N-(2,3-dihydroxybenzoyl)-L-serine
- Iron(III)-[salmochelin S2] complex + H(2)O <=> iron(III)-[salmochelin S1] complex + salmochelin SX
- Iron(III)-[monoglucosyl-(2,3-dihydroxybenzoylserine)(3)] complex + H(2)O <=> iron(III)-[salmochelin S1] complex + N-(2,3-dihydroxybenzoyl)-L-serine
- Iron(III)-[diglucosyl-(2,3-dihydroxybenzoylserine)(2)] complex + H(2)O <=> iron(III)-[salmochelin SX] complex + salmochelin SX
|
Comment(s) |
- This bacterial enzyme is present in pathogenic Salmonella species,
uropathogenic and avian pathogenic Escherichia coli strains,
and certain Klebsiella strains.
- The enzyme acts on iron(III)-bound enterobactin and C-glucosylated
derivatives known as salmochelins.
- Unlike EC 3.1.1.107, (IroE), IroD prefers iron(III)-bound
siderophores as substrates, and is assumed to act after the iron-
siderophore complexes are imported into the cell.
- It catalyzes several hydrolytic reactions, producing a mixture of
iron(III)-(N-(2,3-dihydroxybenzoyl)-L-serine) complex and salmochelin
SX.
|
Cross-references |
BRENDA | 3.1.1.109 |
EC2PDB | 3.1.1.109 |
ExplorEnz | 3.1.1.109 |
PRIAM enzyme-specific profiles | 3.1.1.109 |
KEGG Ligand Database for Enzyme Nomenclature | 3.1.1.109 |
IUBMB Enzyme Nomenclature | 3.1.1.109 |
IntEnz | 3.1.1.109 |
MEDLINE | Find literature relating to 3.1.1.109 |
MetaCyc | 3.1.1.109 |
Rhea expert-curated reactions | 3.1.1.109 |
UniProtKB/Swiss-Prot |
|
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