ENZYME entry: EC 3.1.1.116
Accepted Name |
sn-1-specific diacylglycerol lipase.
|
Reaction catalysed |
A 1,2-diacyl-sn-glycerol + H(2)O <=> a 2-acylglycerol + a fatty acid |
Comment(s) |
- The enzyme, present in animals, is specific for the sn-1 position.
- When acting on 1-acyl-2-arachidonoyl-sn-glycerol, the enzyme forms
2-arachidonoylglycerol, the most abundant endocannabinoid in the
mammalian brain.
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Cross-references |
BRENDA | 3.1.1.116 |
EC2PDB | 3.1.1.116 |
ExplorEnz | 3.1.1.116 |
PRIAM enzyme-specific profiles | 3.1.1.116 |
KEGG Ligand Database for Enzyme Nomenclature | 3.1.1.116 |
IUBMB Enzyme Nomenclature | 3.1.1.116 |
IntEnz | 3.1.1.116 |
MEDLINE | Find literature relating to 3.1.1.116 |
MetaCyc | 3.1.1.116 |
Rhea expert-curated reactions | 3.1.1.116 |
UniProtKB/Swiss-Prot |
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