ENZYME entry: EC 3.1.1.51

PURL: https://purl.expasy.org/enzyme/EC/3.1.1.51

Accepted Name
phorbol-diester hydrolase
Alternative Name(s)
diacylphorbate 12-hydrolase
Reaction catalysed
phorbol 12,13-dibutanoate + H2O = phorbol 13-butanoate + butanoate + H(+)
Comment(s)
Hydrolyzes the 12-ester bond in a variety of 12,13-diacylphorbols (phorbol is a diterpenoid). This reaction inactivates tumor promoter 12-O-tetradecanoylphorbol- 13-acetate from croton oil.
Cross-references
BRENDA	3.1.1.51
EC2PDB	3.1.1.51
ExplorEnz	3.1.1.51
KEGG Ligand Database for Enzyme Nomenclature	3.1.1.51
IUBMB Enzyme Nomenclature	3.1.1.51
MEDLINE	Find literature relating to 3.1.1.51
MetaCyc	3.1.1.51
Rhea expert-curated reactions	3.1.1.51

View entry in original ENZYME format
View entry in raw text format (no links)
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.1.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.1.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.-.-.-