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ENZYME

ENZYME entry: EC 3.1.1.57

Accepted Name
2-pyrone-4,6-dicarboxylate lactonase
Alternative Name(s)
2-pyrone-4,6-dicarboxylate hydrolase
2-pyrone-4,6-dicarboxylate lactonohydrolase
Reaction catalysed
2-oxo-2H-pyran-4,6-dicarboxylate + H2O = (1E)-4-oxobut-1-ene-1,2,4-tricarboxylate + H(+)
Comment(s)
  • The product is most likely the keto-form of 4-oxalmesaconate (shown).
  • It can be converted to the enol-form, 4-hydroxybuta-1,3-diene-1,2,4- trioate, either spontaneously or by EC 5.3.2.8.
Cross-references
BRENDA3.1.1.57
EC2PDB3.1.1.57
ExplorEnz3.1.1.57
PRIAM enzyme-specific profiles3.1.1.57
KEGG Ligand Database for Enzyme Nomenclature3.1.1.57
IUBMB Enzyme Nomenclature3.1.1.57
IntEnz3.1.1.57
MEDLINEFind literature relating to 3.1.1.57
MetaCyc3.1.1.57
Rhea expert-curated reactions3.1.1.57
UniProtKB/Swiss-Prot
Q93PS7, LIGI_COMTEO87170, LIGI_SPHSK

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