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ENZYME

ENZYME entry: EC 3.1.1.89

Accepted Name
protein phosphatase methylesterase-1
Reaction catalysed
[phosphatase 2A protein]-C-terminal L-leucine methyl ester + H2O <=> [phosphatase 2A protein]-C-terminal L-leucine + H(+) + methanol
Comment(s)
  • A key regulator of protein phosphatase 2A.
  • The methyl ester is formed by EC 2.1.1.233.
  • Occurs mainly in the nucleus.
Cross-references
BRENDA3.1.1.89
EC2PDB3.1.1.89
ExplorEnz3.1.1.89
PRIAM enzyme-specific profiles3.1.1.89
KEGG Ligand Database for Enzyme Nomenclature3.1.1.89
IUBMB Enzyme Nomenclature3.1.1.89
IntEnz3.1.1.89
MEDLINEFind literature relating to 3.1.1.89
MetaCyc3.1.1.89
Rhea expert-curated reactions3.1.1.89
UniProtKB/Swiss-Prot
Q4WKB2, PPME1_ASPFUQ2URJ0, PPME1_ASPORQ58DN4, PPME1_BOVIN
Q9BIB3, PPME1_CAEELQ5ALW7, PPME1_CANALQ6FNL6, PPME1_CANGA
P0CO63, PPME1_CRYNBP0CO62, PPME1_CRYNJQ6BZG3, PPME1_DEBHA
Q54TN3, PPME1_DICDIQ5BGN7, PPME1_EMENIQ74Z47, PPME1_EREGS
Q4IQC1, PPME1_GIBZEQ9Y570, PPME1_HUMANQ6CQZ5, PPME1_KLULA
Q8BVQ5, PPME1_MOUSEQ7SGG8, PPME1_NEUCRQ5R4F9, PPME1_PONAB
Q4FZT2, PPME1_RATQ9P7D2, PPME1_SCHPOQ6CGE1, PPME1_YARLI
P38796, PPME1_YEAST

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