Expasy logo

ENZYME

ENZYME entry: EC 3.1.2.31

PURL: https://purl.expasy.org/enzyme/EC/3.1.2.31
Accepted Name
dihydromonacolin L-[lovastatin nonaketide synthase] thioesterase
Reaction catalysed
dihydromonacolin L-[lovastatin nonaketide synthase] + H2O = holo-[lovastatin nonaketide synthase] + dihydromonacolin L carboxylate + H(+)
Comment(s)
  • Dihydromonacolin L acid is synthesized while bound to an acyl-carrier protein domain of EC 2.3.1.161.
  • Since that enzyme lacks a thioesterase domain, release of the dihydromonacolin L acid moiety from the polyketide synthase requires this dedicated enzyme.
Cross-references
Rhea expert-curated reactions3.1.2.31
ExplorEnz3.1.2.31
IUBMB Enzyme Nomenclature3.1.2.31
UniProtKB/Swiss-Prot
Q9Y7C9, LOVG_ASPTEQ0C8M2, LOVG_ASPTNQ3S2U0, MOKD_MONPI
BRENDA3.1.2.31
MetaCyc3.1.2.31
KEGG Ligand Database for Enzyme Nomenclature3.1.2.31
EC2PDB3.1.2.31
MEDLINEFind literature relating to 3.1.2.31

View entry in original ENZYME format
View entry in raw text format (no links)
All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.1.2.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.1.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.-.-.-